摘要
目的研究早期微创颅内血肿清除术治疗高血压脑出血的临床疗效。方法选取2016年5月—2018年4月医院收治的高血压脑出血患者88例,在双盲法下均分为两组,包括对照组和观察组,每组各44例,对照组采用小骨窗血肿清除术,观察组采用早期微创血肿清除术,比较两组临床疗效。结果观察组治疗后的总有效率为93.18%,高于对照组的总有效率77.27%,差异有统计学意义(P <0.05);两组术后7 d、14 d时的白介素-6(IL-6)和肿瘤坏死因子-α(TNF-α)指标水平较术前均有明显变化,但观察组比对照组明显更低(P <0.05);两组术后14 d的神经功能缺损(NIHSS)评分均较术前显著降低,但观察组比对照组改善更明显(P <0.05)。结论临床治疗高血压脑出血采用早期微创颅内血肿清除术能够有效提高临床效果,促进炎症因子水平减轻,显著改善神经功能。
Objective To study the clinical effect of early minimally invasive intracranial hematoma removal in the treatment of hypertensive cerebral hemorrhage.Methods88patients with hypertensive intracerebral hemorrhage admitted to the hospital from May2016to April2018were divided into two groups by double blind method,including control group and observation group,44cases in each group.The control group was treated with small bone window hematoma removal,while the observation group was treated with early minimally invasive hematoma removal.The clinical efficacy of the two groups was compared.Results The total effective rate of the observation group after treatment was93.18%,higher than that of the control group of77.27%(P<0.05).The levels of interleukin-6(IL-6)and tumor necrosis factor-alpha(TNF-alpha)at7and14days after operation in the two groups were significantly changed compared with those before operation,but the level of IL-6and TNF-alpha in the observation group was significantly lower than that in the control group(P<0.05).The scores of neurological deficit(NIHSS)in both groups were significantly lower14days after operation than before,but the improvement in the observation group was more obvious than that in the control group(P<0.05).Conclusion Early minimally invasive removal of intracranial hematoma in the treatment of hypertensive intracerebral hemorrhage can effectively improve the clinical effect,reduce the level of inflammatory factors and significantly improve neurological function.
作者
许磊
廖秋凌
XU Lei;LIAO Qiuling(Department of Emergency,Daye City People's Hospital,Daye Hubei 435100,China)
出处
《中国继续医学教育》
2019年第1期101-104,共4页
China Continuing Medical Education
关键词
早期微创颅内血肿清除术
高血压脑出血
白介素-6
肿瘤坏死因子-Α
疗效
神经功能
early minimally invasive intracranial hematoma clearance
hypertensive cerebral hemorrhage
interleukin-6
tumor necrosis factor –α
curative effect
nerve function
