摘要
目的:分析化疗联合同步放疗治疗胃癌对患者生活和睡眠质量的影响。方法:选取2012年5月至2014年5月福建省肿瘤医院肿瘤内科收治的胃癌患者60例,根据患者入院时间将其随机分为对照组和观察组,每组30例。对照组采用术后化疗方式进行治疗,观察组采用化疗联合同步放疗方式加以治疗,比较2组患者生活和睡眠质量,随访3年统计对比存活率。结果:观察组患者KPS评分降低率11. 76%明显小于对照组的38. 24%(P <0. 05);观察组睡眠质量评分明显低于对照组(P <0. 05或P <0. 01);观察组3年生存率53. 33%明显高于对照组的26. 67%(P <0. 05)。结论:化疗联合同步放疗治疗胃癌可有效提高患者生存率,改善患者睡眠质量,提升生活品质,值得推广。
Objective:To analyze the effect of chemotherapy combined with concurrent radiotherapy on the quality of life and sleep of patients with gastric cancer.Methods:A Total of60cases of gastric cancer patients admitted to our hospital from May2012to May2014were selected and randomly divided into two groups according to the time of admission,30cases in each group.The control group was treated with postoperative chemotherapy,and the observation group was treated with chemotherapy combined with concurrent radiotherapy.The quality of life and sleep of patients in the two groups were compared.Results:The decrease rate of KPS score in the observation group was11.76%,which was significantly lower than38.24%in the control group(P<0.05).The sleep quality score of the observation group was significantly lower than that of the control group(P<0.05or P<0.01).The3-year survival rate of53.33%in the observation group was significantly higher than26.67%in the control group(P<0.05).Conclusion:Chemotherapy combined with concurrent radiotherapy in the treatment of gastric cancer can effectively improve the survival rate of patients,improve the quality of sleep,improve the quality of life of patients,worthy of promotion.
作者
聂铃
陈军
柯熹
Nie Ling;Chen Jun;Ke Xi(Department of oncology, fujian cancer hospital,Fuzhou,350014)
出处
《世界睡眠医学杂志》
2018年第12期1491-1493,共3页
World Journal of Sleep Medicine
关键词
胃癌
化疗
放疗
睡眠质量
Gastric cancer
Chemotherapy
Radiation therapy
The quality of sleep