摘要
综述了3-芳基香豆素在抗人肺癌细胞株A549活性、抗人鼻咽癌细胞株KB活性、抗人乳腺癌细胞株MCF-7活性、抗人气道平滑肌细胞株KV和抗其它肿瘤活性方面的研究进展;通过Perkin反应、Knoevenagel反应、Suzuki偶联反应及其它反应总结了3-芳基香豆素合成方面的研究进展,以期为该类化合物抗肿瘤活性深入研究和开发提供参考。
The research progress of3-aryl coumarins in anti-human lung cancer cell line A549,anti-human nasopharyngeal carcinoma cell line KB,anti-human breast cancer cell line MCF-7,anti-human duct smooth muscle cell line KV and other tumor activities were reviewed.The progress in the synthesis of3-aryl coumarins were summarized by Perkin reaction,Knoevenagel reaction,Suzuki coupling reaction and other reactions,in order to provide a reference for the further study and development of anti-tumor activities of these compounds.
作者
肖春芬
黄秋妹
李永冲
石茗
XIAO Chun-fen;HUANG Qiu-mei;LI Yong-chong;SHI Ming(Guangdong Food and Drug Vocational College,Guangzhou 510520,China)
出处
《广州化学》
CAS
2018年第6期72-78,共7页
Guangzhou Chemistry
基金
广东省医学科学技术研究基金项目(A2017437)
广东食品药品职业学院自然科学研究项目(2016YZ015)
