摘要
目的分析有二胎需求孕妇出现胎儿畸形的发生率及相关影响因素,为优生指导提供参考。方法回顾性分析2015年4月～2018年4月我科收治有二胎需求的5000例孕妇生育记录资料,并对胎儿畸形患病率进行统计,分析孕妇年龄、接触有害物质、不良妊娠结局史以及产检与患病率的关系。结果 5000例生育记录资料中,有胎儿畸形636例,占12.72%。其中死胎患儿186例,排在首位,占3.72%。父母年龄在35岁以上的发病率最高,其中母亲35岁以上胎儿畸形435例,占8.70%;父亲35岁以上胎儿畸形423例,占8.46%。胎儿畸形患病率和孕妇既往畸形儿生产史、不良妊娠结局、产前检查次数、父母烟酒嗜好、父母接触有害物质等密切相关(P<0.01)。结论有二胎需求孕妇应在优生指导下做好受孕前相关准备工作;鼓励适龄生育,积极开展健康教育和围产期的保健工作,提升孕妇的自我保健意识,对降低胎儿畸形发生率具有重要意义。
Objective To investigate the incidence of fetal malformation and related influencing factors in pregnant women with second child demand,and to provide reference for eugenics guidance.Methods A retrospective analysis of the birth record data of5000pregnant women with second child demand admitted to our hospital from April2015to April2018,statistics on the prevalence of fetal malformations,age of pregnant women,exposure to harmful substances,the history of adverse pregnancy outcomes and the relationship between birth control and prevalence were analyzed.Results There were636cases of fetal malformation in5000birth records(12.72%).Among them,186children with stillbirths ranked first,accounting for3.72%.The incidence of parents was the highest when they were over35years old,including435cases of fetal malformation in mothers over35years old,accounting for8.70%,and423cases of fetal malformations in fathers over35years old,accounting for8.46%.The prevalence of fetal malformation was closely related to the history of maternal malformation,the adverse pregnancy outcome,the number of prenatal examinations,the parents'alcohol and tobacco hobbies,and the exposure of parents to harmful substances.There was a statistically significant difference between the groups(P<0.01).Conclusion Pregnant women with second child needs should make preparations before relevant conception under the guidance of eugenics.There are encouraging childbearing at the appropriate age,actively carrying out health education and perinatal health care,and raising the self-care awareness of pregnant women,which is of great significance in reducing the incidence of fetal malformation.
作者
李瑞青
LI Rui-qing(Department of Gynecology,Anyang Family Planning Technical Service Center,Anyang,Henan,455000,China)
出处
《蛇志》
2018年第4期588-590,共3页
Journal of Snake
关键词
优生
二胎需求
胎儿畸形
影响因素
eugenics
second child demand
fetal malformation
influencing factors
