摘要
目的探究2HRZE/4HR方案+薄芝糖肽治疗艾滋病伴继发性肺结核的疗效。方法选取2017年6—12月我院收治的艾滋病伴继发性肺结核患者96例作为本次实验研究对象。根据电脑盲选法分为观察组和对照组。对照组采用2HRZE/4HR方案治疗,观察组在对照组基础上加入薄芝糖肽治疗。对比两组治疗有效率以及艾滋病病毒核酸检测(HIV-RNA)水平。结果观察组治疗有效率为91.67%高于对照组77.08%(P <0.05);治疗前,观察组HIV-RNA水平与对照组对比差异无统计学意义(P> 0.05);治疗后,对照组HIVRNA水平高于观察组,数据对比差异具有统计学意义(P <0.05)。结论 2HRZE/4HR方案联合薄芝糖肽治疗艾滋病伴继发性肺结核疗效显著,有效减少HIV-RNA亚群水平,缓解不适症状。
Objective To investigate the efficacy of 2HRZE/4HR regimen+ganoderma capense glycopeptide in the treatment of AIDS with secondary pulmonary tuberculosis.Methods 96 patients with AIDS secondary pulmonary tuberculosis admitted into our hospital from June 2017 to December 2017 were selected as the experimental subjects.According to the computer blind selection method,it was divided into observation group and control group.The control group was treated with the 2HRZE/4HR regimen,and the control group was treated with the ganoderma capense glycopeptide on the basis of the observation group.The treatment efficiency and the hiv-rna level(HIV nucleic acid detection)were compared between the two groups.Results The effective rate of the observation group was 91.67%higher than that of the control group(77.08%)(P<0.05).Before treatment,the HIV-RNA level of the observation group and the control group,there was no difference in the HIV-RNA level(P>0.05).After treatment,the HIV-RNA level in the observation group was lower than that of in the control group,and the data was significant different(P<0.05).Conclusion 2HRZE/4HR regimen combined with ganoderma capense glycopeptide is effective in the treatment of AIDS with secondary pulmonary tuberculosis,effectively improve the level of HIV-RNA subpopulation and alleviate discomfort.
作者
李伟
王勇
LI Wei;WANG Yong(Internal Five Department,Infectious Disease Prevention and Cure Hospital,Harbin Heilongjiang 150500,China)
出处
《中国卫生标准管理》
2018年第22期74-76,共3页
China Health Standard Management
