摘要
目的比较盐酸纳布啡联合舒芬太尼与单纯舒芬太尼用于腹腔镜子宫切除术患者自控静脉镇痛(PCIA)的效果。方法选择80例腹腔镜子宫切除术患者按数字表法随机分为Ⅰ组(对照组,n=40):采取舒芬太尼PCIA;Ⅱ组(观察组,n=40):采取纳布啡和舒芬太尼PCIA。观察记录两组患者术后2、6、12、24 h的VAS评分和Ramsay评分、24 h内追加应用镇痛药的例数及不良反应发生率。结果Ⅱ组患者手术后各时间点的VAS评分以及术后24 h追加镇痛药例数低于或少于Ⅰ组(P <0.05),Ramsay评分镇静效果明显优于Ⅰ组(P <0.05)。Ⅰ组患者躁动发生率明显高于Ⅱ组(P <0.01)。结论纳布啡联合舒芬太尼用于腹腔镜子宫切除术PCIA的镇痛效果更确切,可减少患者其它镇痛药的需求量。
Objective To compare the efficacy of nalbuphine hydrochloride combined with sufentanil and simple sufentanil in laparoscopic hysterectomy for PCIA.Methods 80 patients with laparoscopic hysterectomy by digital table method were randomly divided into groupⅠ(control group,n=40):take sufentanil for PCIA and groupⅡ(observation group,n=40):take the nalbuphine and sufentanil for PCIA.The VAS score and Ramsay score of time point at 2,6,12,and 24 hours after surgery,the number of cases of additional analgesic drugs within 24 hours and the incidence of adverse reactions were observed and recorded in the two groups.Results GroupⅡof patients after surgery of VAS score at each time point and postoperative 24 h used additional analgesics were inferior to or less than those in groupⅠ(P<0.05),and Ramsay score of the sedative effect were significantly better than that in groupⅠ(P<0.05).Incidence of agitation of patients in groupⅠwas obviously higher than that in groupⅡ(P<0.01).Conclusion The analgesic effect of naborphine combined with sufentanil used in patients undergoing laparoscopic hysterectomy for PCIA is more definite and can reduce the demand for other analgesic drugs in patients.
作者
刘亚军
刘晓芳
冯宇峰
LIU Yajun;LIU Xiaofang;FENG Yufeng(Deparment of Anesthesiology,The People’s Hospital of Kizilsu Kirghiz Autonomous Prefecture,Kizilsu Xinjiang 845350,China;Department of Anesthesiology,Xiamen Maternal and Children Hospital,Xiamen Fujian 361003,China;Department of Anesthesiology,The First Affiliated Hospital of Xiamen University,Xiamen Fujian 361003,China)
出处
《中国卫生标准管理》
2018年第23期119-121,共3页
China Health Standard Management
关键词
盐酸纳布啡
舒芬太尼
静脉镇痛
腹腔镜手术
妇科
子宫切除术
nalbuphine hydrochloride
sufentanil
introvenous anaigesia
laparoscopic surgery
gynecology department
hysterectomy
