摘要
目的探索肺康复治疗联合无创通气对慢性阻塞性肺疾病(慢阻肺)急性加重期患者运动耐力及生活质量的影响。方法 96例慢阻肺急性加重期患者,根据患者的治疗意愿分为对照组和观察组,每组48例。对照组患者给予常规对症支持治疗和无创通气治疗,观察组在对照组基础上给予肺康复治疗。比较两组患者治疗前后的6 min步行距离、生活质量评分以及第1秒用力呼气容积(FEV1)、第1秒用力呼气容积占预计值的百分比(FEV1%pred)、第1秒用力呼气容积与用力肺活量比值(FEV1/FVC)、用力肺活量(FVC)。结果治疗1周后,两组患者的6 min步行距离长于治疗前,差异具有统计学意义(P<0.05);观察组患者6 min步行距离(291.1±26.7)m长于对照组的(269.6±29.5)m,差异具有统计学意义(P<0.05)。治疗1周后,两组患者的FEV1、FEV1%perd、FVC和FEV1/FVC均明显高于治疗前,且观察组患者的FEV1、FEV1%perd、FVC和FEV1/FVC均明显高于对照组,差异具有统计学意义(P<0.05)。治疗1周后,两组患者的生活质量评分均低于治疗前,且观察组生活质量评分明显低于对照组,差异具有统计学意义(P<0.05)。结论肺康复疗法与无创通气的有机结合有助于稳定急性加重期慢阻肺患者的病情,一定程度上能够改善肺功能,提高其生活质量。
Objective To investigate the effect of pulmonary rehabilitation combined with non-invasive ventilation on exercise tolerance and quality of life in patients with acute exacerbation of chronic obstructive pulmonary disease.Methods A total of 96 patients with acute exacerbation of chronic obstructive pulmonary disease were divided by patients’treatment willing into control group and observation group,with 48 cases in each group.The control group received conventional symptomatic supportive therapy and non-invasive ventilation therapy,and the observation group received pulmonary rehabilitation therapy on the basis of the control group.Comparison were made on walking distance,quality of life score,forced expiratory volume in 1 second(FEV1),percent of predicted forced expiratory volume in one second(FEV1%pred),forced expiratory volume in 1 second percentage of forced vital capacity(FEV1/FVC)and forced vital capacity(FVC)before and after treatment between the two groups.Results After 1 week of treatment,both groups had longer 6 min walking distance than those before treatment,and the difference was statistically significant(P<0.05).The observation group had longer 6 min walking distance as(291.1±26.7)m than(269.6±29.5)m in the control group,and the difference was statistically significant(P<0.05).After 1 week of treatment,both groups had obviously higher FEV1,FEV1%pred,FVC and FEV1/FVC than those before treatment,and the observation group had obviously higher FEV1,FEV1%pred,FVC and FEV1/FVC than the control group.Their difference was statistically significant(P<0.05).After 1 week of treatment,both groups had lower quality of life score than those before treatment,and the observation group had obviously lower quality of life score than the control group.Their difference was statistically significant(P<0.05).Conclusion The organic combination of pulmonary rehabilitation therapy and non-invasive ventilation can help stabilize the condition of patients with acute exacerbation of chronic obstructive pulmonary disease,im
作者
万程伟
李银
WAN Cheng-wei;LI Yin(Department of Respiratory Medicine,Ganzhou People’s Hospital,Ganzhou 341000,China)
出处
《中国现代药物应用》
2018年第23期5-7,共3页
Chinese Journal of Modern Drug Application
关键词
肺康复治疗
无创通气
慢性阻塞性肺疾病急性加重期
运动耐力
生活质量
Pulmonary rehabilitation therapy
Non-invasive ventilation
Acute exacerbation of chronic obstructive pulmonary disease
Exercise tolerance
Quality of life
