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女性原发性肺癌的流行病学特征及其危险因素研究 被引量:21

Epidemiological characteristics and risk factors of female patients with primary lung cancer
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摘要 目的系统性分析浙江省舟山市女性肺癌发病的临床流行病学特征,并探讨其相关独立危险因素。方法手术切除并经病理证实的256例女性肺癌患者(观察组),另取来本院体检健康体者196例设为对照组,采用自制表格问卷调查两组有关的暴露史等流行病学信息。通过单因素及多因素Logistic回归,确定女性肺癌发生的独立危险因素。结果主动或者被动吸烟、大量厨房烟雾、不良的工作通风场所、大量职业接触粉尘以及肿瘤家族史均是女性肺癌发生的独立危险因素(均P<0.05)。结论主被动吸烟、厨房烟雾、长期工作通风差、职业粉尘多以及有肿瘤家族史可能增加女性肺癌患病风险。 Objective To systematically analyse the clinical epidemiological characteristics of lung cancer in the female residents of Zhoushan city and to explore the relevant independent risk factors. Methods The observation group included 256 female lung cancer patients who were treated with resection and 196 patients who received physical examination were collected as the control group. Using the uniformm questionnaire, the cases and controls were interviewed about the epidemiological information of related factors, such as exposure history. Univariate and multivariate unconditional logistic regression were used to determine the independent risk factors for female lung cancer.Results Univariate and multivariate unconditional Logistic regression showed that active or passive smoking, substantial kitchen smoke, poor workplace ventilation large occupational exposure to dust and family history of cancer could increase the risk of lung cancer in women(all < 0.05). Conclusions The risk of female lung cancer may increased by active and passive smoking, kitchen smoke, poor long-term work ventilation, occupational dust and family history.
作者 王欢 李予林 陈志军 乐涵波 WANG Huan;LI Yulin;LU Zhijun;LE Hanbo(Zhoushan Hospital,Zhoushan 316021,Zhejiang,China)
机构地区 舟山医院
出处 《现代实用医学》 2018年第11期1433-1436,共4页 Modern Practical Medicine
基金 舟山市医药卫生科技计划项目(2015B09)
关键词 肺肿瘤 女性 流行病学 Lung neoplasm Cancer Females Epidemiolog
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