摘要
目的研究丙戊酸钠与左乙拉西坦联合疗法在脑卒中后癫痫中的应用价值。方法选取2016年4月～2017年10月本院接诊的脑卒中后癫痫患者66例,根据随机数表法将之进行分组:试验组33例患者联用丙戊酸钠与左乙拉西坦进行治疗,对照组33例患者单用左乙拉西坦进行治疗。分析两组临床病症缓解的效果,比较总有效率以及治疗后相关炎性因子变化情况。结果试验组的临床总有效率高于对照组,差异有统计学意义(P <0.05)。试验组治疗后的相关炎性因子水平均低于对照组,组间差异有统计学意义(P <0.05)。结论于脑卒中后癫痫中积极联用丙戊酸钠和左乙拉西坦,有助于患者的恢复。
Objective To study the value of combination therapy with sodium valproate and levetiracetam in post-stroke epilepsy.Methods 66 patients with post-stroke epilepsy who were admitted to the Zhengzhou First People's Hospital from April 2016 to October 2017 were enrolled.The patients were divided into three groups according to the random number table method:33 patients in the experimental group were treated with sodium valproate and Levetiracetam,and 33 patients in the control group were treated with levetiracetam alone.The effects of clinical symptom relief were analyzed,and the total effective rate as well as the changes of related inflammatory factors after treatment were compared.Results The total clinical effective rate of the experimental group was higher than that of the control group,and the difference was statistically significant(P<0.05).The levels of related inflammatory factors in the experimental group were significantly lower than those in the control group,and the difference between the groups was statistically significant(P<0.05).Conclusions Active combination of sodium valproate and levetiracetam in post-stroke epilepsy contributes to patient recovery.
作者
李时光
刘新生
王昆
LI Shi-guang;LIU Xin-sheng;WANG Kun(The first people's Hospital of Zhengzhou,Zhengzhou,Henan,450004,China)
出处
《临床研究》
2018年第12期55-56,共2页
Clinical Research
