摘要
目的探讨窄带成像技术(NBI)联合放大内镜对西宁地区咽喉癌及癌前病变的早期诊断价值。方法选取咽喉癌及癌前病变患者50例,都进行NBI联合放大内镜模式下诊断,并进行病理诊断。结果 50例患者在内镜白光下评分为(2. 41±0. 78)分,而在NBI联合放大内镜模式的评分为(3. 50±0. 61)分,对比差异有统计学意义(P <0. 05)。不同模式下患者的上皮内乳头样毛细血管袢(IPCL)分型对比差异也有统计学意义(P <0. 05),内镜白光模式下多为Ⅰ型与Ⅱ型分型,而NBI联合放大内镜模式下多为Ⅱ型与Ⅲ型分型。内镜白光模式下诊断咽喉癌的敏感度与特异度为85. 7%和84. 2%,而NBI联合放大内镜模式诊断的敏感度与特异度为97. 1%和93. 3%,对比差异都有统计学意义(P <0. 05)。结论 NBI联合放大内镜诊断咽喉癌及癌前病变能清晰显示病变特征,有效判定上皮内乳头样毛细血管袢分型,提高诊断敏感度与特异度,具有很高的临床实用价值。
Objective To explore the early diagnostic value of narrow-band imaging(NBI)combined with magnifying endoscopy for throat cancer and precancerous lesions in Xining.Methods Selecting 50 patients with pharyngocarcinoma and precancerous lesions,all underwent NBI combined with magnifying endoscopic diagnosis and pathological diagnosis.Results 50 patients received a score of(2.41±0.78)for endoscopic white light,and(3.50±0.61)for NBI combined with magnifying endoscopy.The difference was statistically significant(P<0.05).There were significant differences(P<0.05)in patients with intraepithelial papillary capillary loops(IPCL)patterns in different modes.In endoscopic white light mode,there were mostly typeⅠandⅡtypes,and NBI combined with magnifying endoscopy.The patterns were mostly typeⅡand typeⅢ.The magnifying endoscope mode were mostly showedⅠandⅡtypes,and NBI mode were mostly showedⅡandⅢtype classification.The magnifying endoscope diagnosis sensitivity and specificity of laryngopharyngeal carcinoma were 85.7%and 84.2%,while the sensitivity and specificity of NBI diagnosis were 97.1%and 93.3%,the differences were statistically significant(P<0.05).Conclusion NBI for diagnosis of laryngopharyngeal carcinoma and precancerous lesions can clearly show the lesion characteristics,it can effectively determine intraepithelial papillary capillary loop type,it can improve diagnostic sensitivity and specificity that has high clinical values.
作者
熊向菁
王青海
付海生
李俊娟
谢添慧
刘慧
XIONG Xiangjing;WANG Qinghai;FU Haisheng(Xining NO.1 People's Hospital,Xining,810000)
出处
《实用癌症杂志》
2018年第11期1904-1907,共4页
The Practical Journal of Cancer
关键词
内镜窄带成像
咽喉癌
癌前病变
放大内镜
NBI
Laryngopharyngeal carcinoma
Precancerous lesions
Magnifying endoscope
