摘要
目的分析急性缺血性卒中患者住院期间神经功能恶化的影响因素。方法回顾性分析850例急性缺血性卒中患者的临床资料,根据患者病情变化情况将患者分为无再发加重组(n=713)、再发组(n=41)及加重组(n=96),比较3组患者一般资料、既往史、临床评分及实验室检查结果,探讨患者再发或加重的影响因素。结果加重组入院NIHSS评分高于无再发加重组,差异有统计学意义(P <0. 05);再发组ESRS高于无再发加重组,差异有统计学意义(P <0. 05);再发组血小板计数高于无再发加重组及加重组,差异有统计学意义(P <0. 05); TOAST分型中LAA型与SAA型比较,发生再发及加重比例更高,差异有统计学意义(P <0. 05),而其他组别之间差异无统计学意义(P> 0. 05)。结论 NIHSS评分高的患者易加重,ESRS高、血小板计数高、TOAST分型中LAA型较SAA型患者易复发。
Objective To investigate the influencing factors of neurological function deterioration in patients with acute ischemic stroke during hospitalization.Methods The clinical data of 850 patients with acute ischemic stroke who were treated in our hospital from January 2016 to December 2017 were retrospectively analyzed.According to the changes of patients’condition,these patients were divided into no recurrence aggravation group(n=713),recurrence group(n=41)and aggravation group(n=96).The general data,previous history,clinical scores and laboratory examination results were observed and compared among the three groups,moreover,the influencing factors on recurrence or aggravation were analyzed.Results The NIHSS scores in aggravation group were significantly higher than those in no recurrence aggravation group(P<0.05),and ESRS in recurrence group was significantly higher than that in no recurrence aggravation group(P<0.05).Moreover the blood platelet count in recurrence group was significantly higher than that in no recurrence aggravation group and aggravation group(P<0.05).In TOAST typing,as compared with SAA type,there was a higher proportion of LAA type in recurrence aggravation group(P<0.05),however,there was no significant difference among the other groups(P>0.05).Conclusion The patients with high NIHSS scores are easy to be aggratated,and patients with higher ESRS or higher blood platelet count were easy to relapse.And the patients with LAA type are easier to relapse,as compared with the patients with SAA type.
作者
马海蓉
阚丽娟
盛丽琴
蔡秋芳
MA Hairong;KAN Lijuan;SHENG Liqin(Department of Neurology,TCM Hsopital of Kunshan City Affiliated to Nanjing TCM University,Jiangsu,Kunshan 215300,China)
出处
《河北医药》
CAS
2018年第22期3429-3431,3435,共4页
Hebei Medical Journal
