摘要
目的探析尿毒症脑病患者应用血液透析联合血液灌流治疗的效果。方法 2012年10月—2017年10月在该院接受治疗的尿毒症脑病患者中随机选择85例并分为参考组(n=41)和探析组(n=44),所有患者均接受饮食控制治疗、促红细胞生成素以及降压等常规治疗,同时接受血液透析治疗,探析组患者联合应用血液透析、血液灌流治疗。结果探析组总有效率为97.73%,参考组为82.93%,2组疗效差异有统计学意义(χ~2=9.471 2,P=0.021 5)。治疗后探析组患者钾离子明显低于参考组,2组差异有统计学意义(t=8.223 7,P=0.018 9),钠离子明显较参考组患者低,2组差异有统计学意义(t=21.737 2,P=0.002 6),探析组患者肌酐低于参考组,2组差异有统计学意义(t=24.724 7,P=0.037 8),尿素氮低于参考组,2组差异有统计学意义(t=5.273 9,P=0.017 3),β2-微球蛋白低于参考组,2组差异有统计学意义(t=9.725 6,P=0.037 1)。结论尿毒症脑病患者应用血液透析联合血液灌流治疗有助于保持电解质平衡,对于保护患者肾功能以及促进其临床症状改善均可发挥积极作用。
Objective To analyze the effect of hemodialysis combined with blood perfusion therapy in patients with uremia encephalopathy.Methods From October 2012 to October 2017,85 patients with uremic encephalopathy who were treated in the hospital were randomly selected and divided into reference group(n=41)and probing group(n=44).All patients received diet control treatment,erythropoietin and antihypertensive treatment,and hemodialysis treatment,combined with hemodialysis,blood perfusion therapy.Results The total effective rate was 97.73%in the probing group and 82.93%in the reference group.The difference in the efficacy between the two groups was statistically significant(χ2=9.471 2,P=0.021 5).After treatment,the potassium ion in the probing group was significantly lower than that in the reference group.The difference between the two groups was statistically significant(t=8.223 7,P=0.018 9).The sodium ion was significantly lower than that of the reference group.The difference between the two groups was statistically significant(t=21.737 2,P=0.002 6),the creatinine of the patients in the analysis group was lower than the reference group,the difference between the two groups was statistically significant(t=24.724 7,P=0.037 8),the urea nitrogen was lower than the reference group,and the difference between the two groups was statistically significant(t=5.273 9,P=0.017 3),β2-microglobulin was lower than the reference group,and the difference between the two groups was statistically significant(t=9.725 6,P=0.037 1).Conclusion Hemodialysis combined with hemoperfusion in patients with uremia encephalopathy can help maintain electrolyte balance and play an active role in protecting patients'renal function and promoting their clinical symptoms.
作者
周美香
ZHOU Mei-xiang(Department of Nephrology,People's Hospital of Lijiang City,Lijiang,Yunnan Province,674100 China)
出处
《中外医疗》
2018年第29期46-48,共3页
China & Foreign Medical Treatment
关键词
血液透析
血液灌流
尿毒症脑病
Hemodialysis
Blood perfusion
Uremia encephalopathy
