摘要
通过亲核取代反应、Suzuki偶联反应和关环反应合成了二苯并噻吩衍生物,并运用核磁共振(NMR)技术(~1H NMR,^(13)C NMR,~1H-~1H COSY,HSQC,HMBC)研究其结构,且报道了其波谱峰位的归属。通过该实验,学生可以比较完整、系统地了解有机合成的主要步骤与表征方法,并且通过分析NMR谱图,理解核磁共振技术在有机合成中确定未知物的重要作用。
New dibenzothiophene derivative was synthesized,and the chemical structure was studied by NMR(1H NMR,13 C NMR,1H-1H COSY,HSQC,HMBC)techniques.The NMR signals assignment of the target compound were discussed and summarized.Preparation and characterization of a new compound are one of the compulsory experimental courses for the materials science related field student.Consequently,by the experiment,the students can master the main steps and characterization methods of organic synthesis,and realize the important role of nuclear magnetic resonance technique in determining the structure of new compound.
作者
郭婷
王丹
姚日晖
吴为敬
GUO Ting;WANG Dan;YAO Rihui;WU Weijing(School of Materials Science and Engineering,South China University of Technology,Guangzhou 510640,China)
出处
《实验室研究与探索》
CAS
北大核心
2018年第10期54-58,共5页
Research and Exploration In Laboratory
基金
中央高校科研业务费(2017MS020)
关键词
二苯并噻吩
合成
结构表征
核磁共振
dibenzothiophene
synthesis
structure characterization
nuclear magnetic resonance(NMR)
