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帕罗西汀联合奥氮平治疗抑郁症并发睡眠障碍临床效果观察 被引量:14

Clinical effect observation of paroxetine combined with olanzapine in the treatment of depression combined with sleep disorders
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摘要 目的:探讨帕罗西汀联合奥氮平治疗抑郁症并发睡眠障碍的临床效果。方法:收治抑郁症并发睡眠障碍患者66例,随机分为两组。对照组给予帕罗西汀治疗,试验组给予帕罗西汀联合奥氮平治疗,比较两组抑郁症状、临床疗效。结果:试验组治疗后抑郁症状评分明显低于对照组,总有效率明显高于对照组,差异有统计学意义(P<0.05)。结论:帕罗西汀联合奥氮平治疗抑郁症并发睡眠障碍患者可有效改善抑郁症状,临床疗效较好。 Objective:To explore the clinical effect of paroxetine combined with olanzapine in the treatment of depression combined with sleep disorders.Methods:66 cases of patients with depression combined with sleep disorders were divided into two groups randomly.The control group was treated with paroxetine,while the experiment group was treated with paroxetine combined with olanzapine,the depressive symptoms and clinical effect between the two groups were compared.Results:The depressive symptoms score of the experiment group was significantly lower than that of the control group,the total effective rate of the experiment group was significantly higher than that of the control group,and the difference was statistically significant(P<0.05).Conclusion:Paroxetine combined with olanzapine in the treatment of patients with depression combined with sleep disorders could improve depressive symptoms effectively,and the clinical effect was better.
作者 段能 Duan Neng(The Coal Mine Psychiatric Hospital of Yunnan Province 652402)
出处 《中国社区医师》 2018年第31期63-64,共2页 Chinese Community Doctors
关键词 奥氮平 睡眠障碍 帕罗西汀 抑郁症 临床疗效 Olanzapine Sleep disorders Paroxetine Depression Clinical effect
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