摘要
植物神经反射异常是一种多见于T6及以上脊髓损伤人群中的急性病症,慢性脊髓损伤患者中发病率较高,常由损伤平面以下部位刺激诱发。突然的血压升高是主要的临床症状,未经处理的高血压可引起心脑血管意外甚至死亡。植物神经功能紊乱的发病机制可能与脊上调节功能障碍、发生神经可塑性变化以及相关受体发生变化有关。目前治疗及预防措施主要有去除诱因、体位调节及药物治疗。
Autonomic dysreflexia(AD)is an emergency commonly happened in patients with spinal cord injury(SCI)above T6 and especially in chronic SCI patients.AD is usually triggered by stimuli below the injury level.Sudden elevated blood pressure is the main clinical symptom and cardiovascular and/or cerebral complication even death if effective treatments are not provided.Mechanisms contributed to AD possibly are dysfunction of supra spinal control,plastic changes of neurons and receptors.Preventive measures and managements such as removal of risk factor,adjustment of body position,and pharmacological treatment are now in use.
作者
熊巍
苏跃
张军卫
王强
XIONG Wei;SU Yue;ZHANG Jun-wei;WANG Qiang(Department of Anesthesiology,China Rehabilitation Research Center,Beijing 100068,China;Department of Anesthesiology,Beijing Shijitan Hospital,Capital Medical University,Beijing 100038,China;Capital Medical University School of Rehabilitation Medicine,Beijing 100068,China;Department of Spine and Spinal Cord Surgery,Beijing Bo'ai Hospital,China Rehabilitation Research Center,Beijing 100068,China)
出处
《中国康复理论与实践》
CSCD
北大核心
2018年第10期1172-1177,共6页
Chinese Journal of Rehabilitation Theory and Practice
关键词
脊髓损伤
植物神经反射异常
临床特点
机制
处理
综述
spinal cord injury
autonomic dysreflexia
clinical characteristics
mechanism
treatment
review
