摘要
目的探讨埃索美拉唑联合莫沙必利治疗反流性食管炎的临床疗效。方法将54例反流性食管炎患者随机分为观察组28例和对照组26例,对照组给予莫沙必利联合奥拉美唑治疗,观察组应用埃索美拉唑联合莫沙必利治疗,对比两组临床疗效。结果观察组治疗总有效率高于对照组(P<0.05);观察组内镜下症状改善情况优于对照组(P<0.05);观察组不良反应发生率和对照组对比差异无统计学意义(P>0.05)。结论在反流性食管炎的治疗中应用埃索美拉唑联合莫沙必利治疗可以提高临床治疗效果,改善患者症状。
Objective To explore the clinical efficacy of esomeprazole combined with mosapride in the treatment of reflux esophagitis.Methods 54 cases reflux esophagitis patients were randomly divided into observation group of 28 cases and the control group of 26 cases.The control group was treated with Mosapride combined with Orazolazole.The observation group was treated with esomeprazole combined with mosapride.The clinical effects of the two groups were compared.Results The total effective rate of the observation group was higher than that of the control group(P<0.05).The improvement of symptoms in the observation group was better than that in the control group(P<0.05).The incidence of adverse reactions in the observation group was not significantly different from that in the control group(P>0.05).Conclusion In the treatment of reflux esophagitis,the application of esomeprazole combined with mosalbil can improve the clinical therapeutic effect and improve the patient's symptoms.
作者
李世媛
胡定海
LI Shiyuan;HU Dinghai(Third Internal Medicine Department,Dongchuan District People's Hospital of Kunming City,Kunming Yunnan 654100,China;Administrative Office,The Center for Disease Control and Prevention of Dongchuan District of Kunming City,Kunming Yunnan 654100,China)
出处
《中国继续医学教育》
2018年第23期104-106,共3页
China Continuing Medical Education
