摘要
抽动秽语综合征(Tourette's syndrome,TS)是抽动障碍(TD)的严重型,近年来发病率有增高趋势,临床表现复杂多样,对患儿生活质量造成严重影响。现阶段国内外TS仍以药物治疗为主,但传统药物因不良反应多、药物依从性差等,难以有效治疗TS。因此,寻找治疗TS的新药成为研究热点。文章综述了近年来国内外使用氘代丁苯那嗪及左乙拉西坦治疗TS的进展。
Tourette's syndrome(TS)is a severe type of tic disorder(TD).In recent years,the morbidity of TS has been increasing,and the clinical manifestations are complex and diversified,which has a serious impact on the quality of life of children.At present,drug treatment is still the main treatment for TS at home and abroad,but traditional drugs are difficult to effectively treat TS due to multiple adverse reactions and poor drug compliance.Therefore,to find new drugs instead of the treatment of TS has become a research hot spot.This article reviews the recent progress in the use of deuterated tetrabenazine and levetiracetam in the treatment of TS in China and abroad.
作者
马颖君
郝艳秋
MA Yingjun;HAO Yanqiu(The Second Affiliated Hospital of Harbin Medical University,Harbin 150000,Heilongjiang,China)
出处
《临床儿科杂志》
CAS
CSCD
北大核心
2018年第9期720-723,共4页
Journal of Clinical Pediatrics