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血常规筛查对静止型α-地中海贫血的诊断价值 被引量:1

Diagnostic value of blood routine screening in static patients with α-thalassemia
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摘要 目的:评估血常规检测对静止型α-地中海贫血的诊断价值。方法:以240例α-地中海贫血患者(观察组)和110例健康体检者(对照组)作为研究对象,检测两组对象的血红蛋白(hemoglobin,Hb)、平均红细胞体积(mean corpuscular volume,MCV)、平均红细胞血红蛋白含量(mean corpuscular hemoglobin,MCH),分析各指标的诊断价值。结果:各型α地中海贫血患者Hb、MCV、MCH均低于对照组(P<0.05);各指标单独检测静止型α-地中海贫血患者的灵敏度和准确度较低,三者联合检测,灵敏度和准确度均有所提高(P<0.05)。结论:临床上对静止型α-地中海贫血患者进行筛查时,应联合Hb、MCV、MCH指标进行筛查,以降低漏检率。 Objective:To evaluate the diagnostic value of blood routine screening in staticα-thalassemia patients.Methods:240 cases of patients withα-thalassemia(observation group)and 110 cases of healthy people(control group)were selected as the research objects,and the blood indexes of Hb,MCV and MCH in the two groups were detected and their diagnostic value of each index was analyzed.Results:Hb,MCV and MCH of patients withα-thalassemia were significantly decreased compared with those in the control group(P<0.05).The sensitivity and accuracy of individual analysis of each indicator had obvious leakage.The detection results of the combined analysis of Hb,MCV and MCH were significantly improved(P<0.05).Conclusion:In the screening of patients with staticα-thalassemia,Hb,MCV and MCH detection should be combined to reduce the leakage rate.
作者 陈奕微 迟绍琴 许育君 CHEN Yiwei;CHI Shaoqin;XU Yujun(Maternal and Child Health Care Hospital of Longgang District of Shenzhen City,Shenzhen 518172,China;People's Hospital of Longgang District of Shenzhen City)
出处 《包头医学院学报》 CAS 2018年第7期29-31,共3页 Journal of Baotou Medical College
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