摘要
目的:探讨老年缺血性脑卒中病变部位与卒中后抑郁的关系。方法:以86例老年缺血性脑卒中患者为研究对象,将51例卒中后未发生抑郁的患者分为A组,35例卒中后抑郁的患者分为B组,比较两组患者脑梗死灶的部位、侧别、体积以及数目;比较不同抑郁程度患者的梗死灶体积和数目。结果:86例老年缺血性脑卒中患者的卒中后抑郁发生率为40.7%(35/86);B组患者梗死灶位于额叶、颞叶的比例均高于A组,而梗死灶位于基底节区的比例低于A组(P<0.05),梗死灶位于额叶、颞叶是老年缺血性脑卒中并发卒中后抑郁的危险因素;两组患者梗死灶侧别比较,差异无统计学意义(P>0.05);B组患者梗死灶体积和梗死灶数目均高于A组(P<0.05);轻度、中度以及重度抑郁患者梗死灶体积、梗死灶数目组间比较,差异有统计学意义(P<0.05)。结论:老年缺血性脑卒中患者卒中后抑郁的发病风险较高,额叶、颞叶梗死是卒中后抑郁发病的危险因素,卒中后抑郁严重程度与梗死灶体积、数目有关。
Objective:To explore the relationship between the lesion location of ischemic stroke in the elderly and the post stroke depression.Methods:86 elderly patients with ischemic stroke were chosen and divided into Group A(51 patients without depression after stroke)and Group B(35 patients with post stroke depression),with the lesion locations,the lateral infarcts,the volumes and the numbers of infarcts compared between the two groups and the volumes and numbers of infarcts compared among the patients with different depressive degree.Results:The incidence of post-stroke depression in 86 elderly patients with ischemic stroke was 40.7%(35/86).The proportion of infarcts located in frontal and temporal lobes in Group B was significantly higher than that in Group A while the proportion of infarcts in basal ganglia in Group B was significantly lower than that in group A(P<0.05).The infarcts located in the frontal and temporal lobes were the risk factors for post stroke depression in elderly patients.There was no significant difference in lateral infarcts between the two groups(P>0.05).The volumes and the numbers of infarcts in Group B were significantly larger than those in Group A(P<0.05).There was significant difference in infarct volumes and the numbers of infarcts between mild,moderate and severe depression patients(P<0.05).Conclusion:The risk of post stroke depression in elderly patients with ischemic stroke is high.The infarcts located in the frontal and temporal lobe are risk factors for post stroke depression.The severity of post-stroke depression is related to the volumes and the numbers of infarcts.
作者
翟青玲
曹淑华
ZHAI Qingling;CAO Shuhua(Hospital of Traditional Chinese and Western Medicine,Guangdong,Foshan 528200,China)
出处
《包头医学院学报》
CAS
2018年第7期11-12,24,共3页
Journal of Baotou Medical College
关键词
老年缺血性脑卒中
病变部位
卒中后抑郁
Ischemic stroke in the elderly
Lesion location
Post stroke depression
