摘要
内毒素是革兰氏阴性杆菌细胞壁中的一种成分,叫做脂多糖,脂多糖对宿主有毒性作用。内毒素在社区获得性肺炎患者中的作用不容忽视,尤其是伴有高热、白细胞升高、全身炎症反应综合症的老年和危重症患者。近年来研究证实血必净可拮抗内毒素,降低内毒素引发的血清TNF-α水平,在社区获得性肺炎的治疗中疗效可靠。本文就血必净治疗社区获得性肺炎作用机制及临床应用效果作一综述。
Endotoxin is a component of the Gram-negative bacilli cell wall,called lipopolysaccharide,lipopolysaccharide toxic effects on the host.The role of endotoxin in patients with community-acquired pneumonia should not be overlooked,especially in elderly and critically ill patients with fever,leukocytosis,and systemic inflammatory response syndrome.In recent years,studies have shown that Xuebijing can antagonize endotoxin,reduce endotoxin-induced serum levels of TNF-α,in the treatment of community-acquired pneumonia curative effect is reliable.This article reviews the mechanism of Xuebijing in treating community-acquired pneumonia and its clinical application.
作者
赵建美
邵岩
ZHAO Jian-mei;SHAO Yan(Department of Internal Medicine,Tianjin Binhai New Area Hospital of Traditional Chinese Medicine,Tianjin 300451,China)
出处
《医学信息》
2018年第2期20-22,共3页
Journal of Medical Information
基金
天津市科技计划项目(编号:15ZXLCSY00020)
