摘要
目的研究红霉素治疗小儿喘息性肺炎的效果。方法选择我院2014年10月~2017年10月收治的喘息性肺炎患儿60例,按照随机数字表法分为对照组与研究组各30例。对照组采用对症治疗,研究组采用红霉素治疗。比较两组患儿临床症状消失时间、治疗效果与不良反应。结果对照组咳嗽消失时间、肺啰音消失时间以及平均住院时间均长于研究组,研究组93.33%病情缓解率显著由于由于对照组66.67%,研究组6.67%不良反应显著少于对照组26.67%,差异有统计学意义(P<0.05)。两组患儿治疗前血清TNF-α、IL-6水平无显著变化(P>0.05),治疗后,研究组显著优于对照组,且两组组间治疗前后比较差异有统计学意义(P<0.05)。结论通过对小儿喘息性肺炎使用红霉素治疗,患儿基本症状能够在最短时间内恢复正常,抗炎效果较高,不良反应较低,有利于儿童的成长与发育。
Objective To study the clinical effect of erythrocin in children with asthmatic pneumonia.Methods Sixty children with asthmatic pneumonia treated from October 2014 to October 2017 in our hospital were selected.The subjects were randomly divided into two groups,30 cases in each group according to the random number table method.The control group took the symptomatic treatment,the study group was treated with erythrocin.The disappearance time of clinical symptoms,clinical effect and adverse reactions of two groups were compared.Results The disappearance time of cough and lung rale and average hospitalization time of control group were longer than those of study group,the relief rate of study group(93.33%)was significantly higher than that of control group(66.67%),the adverse event rate of study group(6.67%)was significantly lower than that of control group(26.67%),the difference was significant,P<0.05.Before treatment,the level of TNF-αand IL-6 of two groups were not significantly different(P>0.05),after treatment,the level of TNF-αand IL-6 of study group were significantly better than that before and that of control group(P<0.05).Conclusion For children with asthmatic pneumonia,erythrocin can shorten the recovery time of clinical symptoms,improve the anti-inflammation effect,reduce the adverse event rate and promote their growth and development.
作者
彭升
何洲
古超群
杨三珍
郭明春
PENG Sheng;HE Zhou;GU Chaoqun;YANG Sanzhen;GUO Mingchun(Department of Pediatrics,the People's Hospital of Gaozhou City,Gaozhou 525200,China)
出处
《中国医药科学》
2018年第12期58-60,92,共4页
China Medicine And Pharmacy
关键词
红霉素
抗炎
喘息性肺炎
不良反应
Erythrocin
Anti-inflammation
Asthmatic pneumonia
Adverse reactions
