摘要
目的分析角膜肿物患者的临床及病理学特征。方法收集2002年1月至氉2016年6月天津市眼科医院存档的135例(136眼)患者角膜肿物病例资料进行回顾性分析。分析患者的临床特征和肿物的病理学特点。结果在135例角膜肿物患者中,良性肿物共118例(87.41%),包括角膜皮样瘤100例、角膜上皮细胞增生8例、角膜缘色素痣6例、鳞状上皮乳头状瘤2例、上皮细胞性囊肿1例及肉芽组织增生1例;癌前病变及恶性肿瘤共有17例(12.59%),包括日光性角化病5例、鳞状细胞癌5例、原位癌4例、不典型增生3例。5例鳞状细胞癌中有2例乳头状鳞状细胞癌和3例浸润性鳞状细胞癌。角膜良性肿物在0～17岁患者组中发病率最高,角膜癌前病变及恶性肿瘤在60岁及以上患者组中发病率最高。结论角膜肿物中角膜皮样瘤是最常见的角膜良性肿物,日光性角化病是最常见的角膜癌前病变,鳞状细胞癌为最多见的角膜恶性肿瘤。
Objective To analyze the clinical features and pathological classification of corneal neoplasms.Methods The clinical data of 135 patients(136 eyes)of corneal neoplasm between January 2002 and June 2016 in Tianjin Eye Hospital were reviewed retrospectively,and the pathological features were analyzed.Results Together 118 patients(87.41%)with benign neoplasms were found,including 100 patients with corneal dermoid neoplasms,8 patients with epithelium cell proliferation,6 patients with corneal nevus pigmentation,2 patients with squamous papilloma,1 patient with epithelial cyst,1 patient with proliferation of granulation tissue.And 17 patients(12.59%)with premalignant or malignant neoplasms were found,including 5 patients with actinic keratosis,5 patients with squamous cell carcinoma,4 patients with carcinoma in situ,3 patients with atypical hyperplasia.In 5 cases of squamous cell carcinoma patients,there were 2 cases of patients with papillary squamous cell carcinoma and 3 with invasive squamous cell carcinoma.The incidence of benign corneal neoplasms was highest in patients aged 0 to 17 years,and the prevalence of precancerous lesions and malignancies was highest in patients over 60 years of age.Conclusion In patients with corneal neoplasm,corneal dermoid neoplasm is the most common benign tumor of the cornea,and actinic keratosis and squamous cell carcinoma are the most common corneal precancerous lesions and malignancies accordingly in our study.
作者
赵云
于莎莎
林锦镛
赵红
ZHAO Yun;YU Sha-Sha;LIN Jin-Yong;ZHAO Hong(From the Tianjin Eye Hospital and Institute,Clinical College of Ophthalmology of Tianjin Medical University,Tianjin Key Laboratory of Ophthalmology and Vision Science,Tianjin 300020,China)
出处
《眼科新进展》
CAS
北大核心
2018年第5期468-470,共3页
Recent Advances in Ophthalmology
关键词
角膜肿瘤
病理
良恶性肿瘤鉴别
corneal neoplasm
pathology
benign and malignant differentiation
