摘要
中枢神经系统原始神经外胚层肿瘤(PNET)为罕见的恶性肿瘤,术前明确诊断较困难。本文报道1例位于幕下的患者,并汇总2000年至今国内报道的中枢神经系统PNET的文献,统计结果显示其幕上发病占比最高,好发于额叶,男性多于女性,儿童多于成人。该疾病病程短、病死率高,高度恶性,易复发、转移,预后极差。其发病机制尚未完全清楚。对于此疾病需要进一步深入研究,扩大数据量进行分析汇总,对该疾病认识进一步加深,以便于对其病理、病机有更深入地认识,从而提高其诊断、治疗水平,有效提高此类患者的生存质量。
Primitive neuroectodermal tumor(PNET)in the central nervous system is a rare malignant tumor.It is difficult to make a clear diagnosis pre-operatively.This paper reported 1 subtentorial case,and summarized the PNET in the central nervous system that had been reported in the literature in China since 2000.Statistics showed that the incidence of supratentorial cases accounted for the highest and it often occurred in the frontal lobe,and was more commonly seen in male than female,and in children than adults.The disease had short course with high mortality and malignancy.It was easy to relapse and metastasize,and the prognosis was very poor.The pathogenesis of the disease was not completely clear.This disease need profound study and a large amount of data to make analysis and further deepen the understanding of the disease,in order to have a better understanding of the pathology and pathogenesis,thereby improving the diagnosis and treatment level,and promoting the patients′quality of life.
作者
张晓阳
ZHANG Xiao-yang(Department of Neurosurgery,the People's Hospital in Hebei Province,Shijiazhuang 050000,China)
出处
《中国当代医药》
2018年第9期158-161,共4页
China Modern Medicine
