摘要
目的探讨子宫动脉化疗栓塞在宫颈癌手术治疗中的临床价值。方法收集我院2014年3月~2016年8月收治的临床分期Ⅱa~Ⅱb期的宫颈癌患者30例作为研究组,采用先子宫动脉化疗栓塞治疗后行宫颈癌根治手术的方案;选择30例同期直接进行宫颈癌根治术的患者作为对照组。分析近期疗效、肿瘤缩小情况、术中出血量、手术时间及术后病理结果。结果介入治疗后患者的临床症状均有不同程度的缓解,缓解率为100%,介入治疗近期总有效率为76.67%。研究组Ⅱa期和Ⅱb期之间的介入治疗有效率比较,差异无统计学意义(P>0.05)。研究组介入治疗后瘤体直径小于介入治疗前,差异有统计学意义(P<0.05)。研究组患者的术中出血量少于对照组,术后淋巴结转移率、脉管癌栓率、宫旁浸润率均低于对照组,差异有统计学意义(P<0.05)。结论宫颈癌根治手术前行介入治疗能有效缩小肿瘤大小,近期效果显著,改善患者的临床症状,有效抑制淋巴结癌转移、脉管癌栓、宫旁浸润,并降低手术风险。
Objective To explore the clinical value of uterine arterial chemoembolization in the treatment of cervical carcinoma.Methods Thirty patients with cervical cancer of stageⅡa-Ⅱb treated in our hospital from March 2014 to August 2016 were selected as the study group,who underwent radical hysterectomy followed by uterine arterial chemoembolization.Thirty patients who underwent radical resection of cervical cancer at the same period were selected as the control group.The short-term efficacy,tumor shrinkage,the volume of intraoperative blood loss,operation time and postoperative pathological results were analyzed.Results After interventional treatment,the clinical symptoms of patients were relieved in different degrees,the remission rate was 100%,and the total effective rate of short-term curative effect for interventional therapy was 76.67%.There was no significant difference in the effective rate of intervention between study group at stageⅡa andⅡb(P>0.05).The tumor diameter in the study group after interventional treatment was lower than before intervention,and the difference was statistically significant(P<0.05).The volume of intraoperative blood loss in the study group was less than that in the control group,and the rate of cancer metastasis of lymph node,vascular tumor thrombus and para uterine infiltration after operation were all lower than those in the control group,and the difference was statistically significant(P<0.05).Conclusion Interventional therapy before radical resection of cervical cancer can effectively reduce the size of tumor,the short-term curative effect is obvious,and can improve the clinical symptoms of patients,effectively inhibit the cancer metastasis of lymph node,vascular tumor thrombus,and para uterine invasion,and reduce the risk of operation.
作者
丁林康
刘兵元
蒋力平
DING Lin-Kang;LIU Bing-Yuan;JIANG Li-Ping(Intervention Room of Radiological Department,the First Affiliated Hospital of Shihezi University,Xinjiang Uygur Autonomous Region,Shihezi 832000,China)
出处
《中国当代医药》
2018年第9期16-19,共4页
China Modern Medicine
关键词
宫颈癌
新辅助化疗
子宫动脉化疗栓塞
介入治疗
Cervical carcinoma
Neoadjuvant chemotherapy
Chemoembolization of uterine artery
Interventional therapy
