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甘草用于预防气管插管全身麻醉术后病人咽喉痛和咳嗽效果的Meta分析 被引量:7

Meta-analysis of effects of licorice on prevention of sore throat and cough in patients undergoing general anesthesia after tracheal intubation
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摘要 [目的]系统评价甘草预防气管插管全身麻醉术后咽喉痛和咳嗽的效果。[方法]计算机检索Cochrane Library、PubMed、EMBASE、Web of Science、中国生物医学文献数据库(CBM)、万方数据资源系统、中国知网(CNKI)和维普等国内外数据库中有关甘草对预防气管插管全身麻醉术后咽喉痛和拔管后咳嗽的随机对照试验。按照纳入和排除标准筛选文献,提取资料并评价质量,采用RevMan5.3软件进行Meta分析。[结果]共纳入5项随机对照试验,涉及490例研究对象。Meta分析结果显示术前应用甘草漱口液或含片可以降低病人术后休息状态咽喉痛发生率、吞咽状态咽喉痛发生率、拔管时咳嗽发生率,拔管后24h咳嗽发生率;但对于术后其他时间段,甘草预防咳嗽效果未显示出优势。[结论]术前应用甘草有助于预防气管插管全身麻醉术后咽喉痛、咳嗽的发生。 Objective:A systematic review of the efficacy of licorice against sore throat and cough after general anesthesia with endotracheal intubation.Method:Computer based retrieval of randomized controlled trials of licorice to prevent sore throat and cough after extubation after general anesthesia for endotracheal intubation in domestic and foreign databases such as Cochrane Library,PubMed,EMBASE,Web of Science,China Biomedical Literature Database(CBM),Wanfang Data Resource System,CNKI,and VIP.The literature was screened according to inclusion and exclusion criteria,data were extracted and evaluated for quality,and Meta analysis was performed using RevMan 5.3 software.Results:A total of 5 randomized controlled trials were included with a total of 490 subjects.Meta analysis results showed that the preoperative application of licorice mouthwash or lozenges can reduce the incidence of postoperative restless sore throat,the incidence of swallowing sore throat,the incidence of coughing during extubation,and the incidence of coughing up to 24 hours after extubation;however,for other postoperative periods,licorice had no advantage in preventing cough.Conclusions:Preoperative use of licorice helps prevent postoperative complications such as sore throat and cough after general anesthesia for tracheal intubation.
作者 崔楚云 宫尚群 金昌德 Cui Chuyun;Gong Shangqun;Jin Changde(Graduate School of Tianjin University of Traditional Chinese Medicine,Tianjin 300193 China)
出处 《护理研究》 北大核心 2018年第8期1255-1262,共8页 Chinese Nursing Research
关键词 甘草 全身麻醉 咽喉痛 咳嗽 预防 META分析 licorice general anesthesia sore throat cough prevention Meta analysis
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