摘要
目的对慢性肾脏病(CKD)维持血液透析(HD)患者便秘的发生情况及其相关因素进行调查。方法根据RomeⅢ诊断标准制作调查表,选取2016年3月该院行HD患者进行问卷调查,了解其便秘的发生情况,并探讨其相关因素。结果共调查206例HD患者,193例应答,应答率为93.7%;便秘发生率为34.2%。单因素分析结果显示,HD充分性(Kt/V)、血清硫酸吲哚酚(IS)水平、每日蔬菜摄入量、进食蔬菜、水果及运动习惯与HD患者便秘相关。逐步多因素Logistic回归分析提示,IS水平[OR=1.051(95%CI:1.009,1.095)]和Kt/V[OR=0.264(95%CI:0.074,0.945)]是HD患者发生便秘的主要影响因素。结论 HD患者有较高的便秘发生率。IS蓄积是HD患者发生便秘的危险因素,而较高的Kt/V则是保护因素。
Objective To investigate the prevalence of constipation and risk factors in hemodialysis patients.Methods Based on Rome III,questionnaire about bowl evacuation habi twere sent out to patients on chronic hemodialysis in March 2016.Results Totally 193 out of 206 patients were inquired and responded(93.7%).The incidence of constipation was 34.2%.Single factor analysis showed that dialysis adequacy(Kt/V),serum indoxyl sulfate(IS),daily intake of vegetables,frequency of eating vegetables and fruits and frequency of exercises affected the development of constipation.Multivariate logistic regression analysis suggested that serum IS level and Kt/V were independent factors of constipation.Conclusions High prevalence of constipation in chronic hemodialysis patients exists and increased level of IS is risk factor while higher level of Kt/V is protective factor for conatipation.
作者
吴禹池
张上鹏
尹自长
邹川
林启展
Yu-chi Wu;Shang-peng Zhang;Zi-chang Yin;Chuan Zou;Qi-Zhan Lin(Department of Hemodialysis,the Second Affiliated Hospital of Guangzhou University of Chinese Medicine,Guangzhou,Guangdong 510120,China;the Second Medical College of Guangzhou University of Chinese Medicine,Guangzhou,Guangdong 510405,China;Kingmed Pathology Center,Guangzhou,Guangdong 510180,China)
出处
《中国现代医学杂志》
CAS
2018年第12期58-62,共5页
China Journal of Modern Medicine
基金
广东省中医药局2015年度建设中医药强省科研课题(No:20151250)
关键词
慢性肾脏病
血液透析
便秘
硫酸吲哚酚
横断面调查
chronic kidney disease
hemodialysis
constipation
indoxyl sulfate
cross-sectional study
