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膀胱部分切除与经尿道膀胱肿瘤切除术治疗膀胱癌的临床疗效对比 被引量:2

A Comparative Research on the Clinical Efficacy Between Partial Cystectomy and Transurethral Resection of Bladder Tumor in Treatment of Bladder Cancer
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摘要 目的比较膀胱部分切除与经尿道膀胱肿瘤切除术治疗膀胱癌的临床疗效。方法方便选取2014年1月—2016年6月该院收治的膀胱癌患者88例,对其临床资料进行回顾性分析。其中43例患者接受膀胱部分切除治疗,将其设定为对照组,45例患者接受经尿道膀胱肿瘤切除术治疗,将其设定为观察组。比较两组手术情况,术后并发症发生情况以及肿瘤复发情况。结果经过相应方式治疗后,观察组术中出血量为(52.6±7.3)m L,少于对照组的86.8±10.3)m L,差异有统计学意义(t=18.034,P<0.05);观察组手术时间为(53.5±3.9)min、留置导尿管时间为(6.3±2.6)d、膀胱冲洗时间为(17.2±3.8)min、住院时间为(8.8±2.9)d,短于对照组的手术时间(83.6±4.8)min、留置导尿管时间(10.1±2.8)d、膀胱冲洗时间(27.6±3.8)min、住院时间(13.8±5.1)d,差异有统计学意义(t=32.352、6.601、12.834、5.686,P<0.05);观察组血钠降低发生率为6.67%,无膀胱穿孔发生,低于对照组的血钠降低发生率23.26%和膀胱穿孔发生率9.30%,差异均有统计学意义(χ2=4.806、4.004,P<0.05);对照组肿瘤复发率为23.26%;观察组肿瘤复发率为13.33%,差异无统计学意义(χ2=1.455,P>0.05)。结论膀胱部分切除和经尿道膀胱癌切除术均可有效治疗膀胱癌,但相较之下后者可取得更为显著的治疗效果,同时不会对机体造成较大的手术创伤,具备更高的临床普及价值。 Objective To compare the clinical efficacy between partial cystectomy and transurethral resection of bladder tumor in the treatment of urinary cancer patients.Methods 88 cases of bladder cancer patients in our hospital from Jan.2014 to Jun.2016 were convenient selected,the clinical data of the patients were retrospectively analyzed.43 cases of patients who underwent partial cystectomy as the control group.45 cases of patients who underwent transurethral resection of bladder tumor as the observation group.The the operation circumstances,postoperative complications and tumor recurrences between the two groups were compared.Results After the corresponding treatment,the bleeding volume in the observation group was(52.6±7.3)mL,which was less than(86.8±10.3)mL in the control group,the difference was statistically significant(t=18.034,P<0.05);The operation time was(53.5±3.9)min,catheterization time was(6.3±2.6)d,bladder irrigation time was(17.2±3.8)min,hospitalization time was(8.8±2.9)d in the observation group,which was shorter than the operation time(83.6±4.8)min,indwelling catheter time(10.1±2.8)d,bladder irrigation time(27.6±3.8)min and hospitalization time(13.8±5.1)d in the control group respectively,the differences were statistically significant(t=32.352,6.601,12.834,5.686,P<0.05).The incidence of hyponatremia was 6.67%and no ladder perforation in the observation group,which was lower than the incidence of hyponatremia(23.26%)and incidence of bladder perforation(9.30%)in the control group respectively,the differences was statistically significant(χ2=4.806,4.004,P<0.05).The tumor recurrence rate in the observation group and control group was 13.33%and 23.26%respectively,the difference was no significant(χ2=1.455,P>0.05).Conclusion Both of partial cystectomy and transurethral resection of bladder tumor have a significant effect for the treatment of bladder cancer,whilr the latter method can achieve more significant therapeutic effect and has less surgical trauma,it has higher clinical popularization val
作者 杨向利 刘磊 黎妮 YANG Xiang-li;LIU Lei;LI Ning(Department of Urology,the Affiliated Hospital of Wuhan University of Science Technology,Wuhan,Hubei,Province,430064 China;Department of Neurosurgery,the Affiliated Hospital of Wuhan University of Science Technology,Wuhan,Hubei,Province,430064 China;.Department of Nephrology,The Central Hospital of Wuhan,Wuhan,Hubei,Province 430000 China)
出处 《中外医疗》 2018年第5期57-60,共4页 China & Foreign Medical Treatment
关键词 膀胱癌 膀胱部分切除 经尿道膀胱肿瘤切除术 临床疗效 Bladder cancer Partial cystectomy Transurethral resection of bladder tumor Clinical efficacy
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