摘要
目的探究轻度认知功能障碍患者中医体质分型与发病之间的关系。方法随机选取2015年1月-2016年12月在新疆医科大学附属中医医院就诊的60~85岁患者进行认知功能评定,随机选取轻度认知功能障碍(MCI)患者300例为病例组,认知功能正常者300例为对照组。依据中华中医药学会体质分会制定的《中医体质分类与判定》(2009年)九分法标准对所有患者进行中医体质分型判定。体质分型数据采用pearson卡方检验进行统计学分析。结果对与照组比较,病例组患者中医体质分布差异有统计学意义(χ~2=47.752,P=0.000)。病例组患者气虚质(126例)、特禀质(15例)、阳虚质(60例)高于对照组气虚质(86例)、特禀质(2例)、阳虚质(35例),差异有统计学意义(P<0.05);病例组患者气郁质(21例)、阴虚质(14例)低于对照组气郁质(39例)、阴虚质(41例),差异有统计学意义(P<0.05);患病比例较高的中医体质依次为特禀质(88.2%)、阳虚质(63.2%)、气虚质(58.6%),与其他6种中医体质类型患者发病率相比,差异有统计学意义(P均<0.05)。结论 MCI患者中气虚质、阳虚质、痰湿质体质患者较多,且每种证型患病率比较,特禀质、阳虚质、气虚质体质患者较高。
Objective To study the relationship between TCM Constitution and pathogenesis in patients with mild cognitive impairment.Methods The patients aged 60-85 years from the Affiliated Traditional Chinese Medicine Hospital of Xinjiang Medical University during January 2015-December 2016 were randomly selected,and accessed the cognitive function.300 cases of mild cognitive impairment(MCI)patients were selected as case group,and 300 cases with normal cognitive function were the control group.The constitution classification of the Chinese medicine was determined on all patients.The final data were analyzed by Pearson chi square test.Results Compared with the control group,the patients in the case group were higher in Qi deficiency,special quality and Yang deficiency,and the difference was statistically significant(P<0.05).The Qi stagnation and Yin deficiency were low,and the difference was statistically significant(P<0.05).The higher proportion of TCM constitution were sequentially natural endowment(88.2%),Yang deficiency(63.2%),Qi deficiency(58.6%),and there were significant differences compared with the other 6 TCM constitution types,and the differences were statistically significant(P<0.05).Conclusion The quantities of MCI patients with Qi deficiency,Yang deficiency and phlegm dampness were more,and the prevalence rates of that were higher,in which Yang deficiency and Qi deficiency were higher than other types.
作者
孙薇
张倩
杨建波
徐金凤
林晓静
魏建刚
王蓉
张小宁
SUN Wei;HANG Qian;YANG Jianbo;XU Jinfeng;LIN Xiaojing;WEI Jiangang;WANG Rong;ZHANG Xiaoning(Department of Internal Medicine-Neurology,the Affiliated traditional Chinese Medical Hospital of Xinjiang Medical University,Urumqi 830000,China)
出处
《新疆医科大学学报》
CAS
2018年第4期502-504,509,共4页
Journal of Xinjiang Medical University
基金
新疆维吾尔自治区自然科学基金青年基金项目(2015211C158)
关键词
轻度认知功能障碍
中医体质分型
调查研究
mild cognitive impairment
TCM constitution classification
investigation and study
