摘要
目的探索癌因性疲乏(cancer related fatigue,CRF)发生的影响因素。方法采用问卷调查的方法,依照国际疾病分类标准第10版癌因性疲乏的定义,对符合纳入/排除标准的肺癌患者进行分组,分析社会人口学特征、临床指标及心理因素对CRF的影响。分析癌因性疲乏的独立影响因素。结果最终纳入肺癌患者242例,疲乏组162人,非疲乏组80人。单因素分析显示,性别、年龄、血红蛋白水平、白细胞计数、家庭月收入、焦虑情绪、抑郁情绪均与癌因性疲乏有关。经多元Logistic回归分析后,年龄、性别、家庭月收入、白细胞计数、血红蛋白水平、焦虑情绪为癌因性疲乏的独立影响因素。结论年龄、性别、焦虑情绪是癌因性疲乏的危险因素,家庭月收入、血红蛋白水平、白细胞计数是其保护性因素。
Objective To analyze factors in the occurrence of cancer related fatigue(CRF)from the sociodemographic characteristics,clinical indicators,psychological factors.Methods In accordance with the definition of cancer related fatigue in international classification of diseases(10th edition),we adopted questionnaire and grouped 242 lung cancer patients meeting inclusion and exclusion criteria in Gansu,and analyzed the impact of sociodemographic characteristics,clinical indicators and psychological factors on CRF.The independent factors of cancer-related fatigue were explored.Results According to the inclusion/exclusion criteria,242 valid questionnaires were completed,and the final statistical cases were 162 in the fatigued group and 80 in the non-fatigued group.Univariate analysis showed that gender,age,hemoglobin level,white blood cell count,family income,anxiety and depression were all associated with CRF.After multivariate logistic regression analysis,the aforementioned fatorsare all independent factors for CRF.Conclusion Age,gender and anxiety are risk factors of cancer-related fatigue,while family income,hemoglobin level and white blood count are protective factors.
作者
李朝霞
米登海
温志震
余新林
邵鹏
王永翔
Li Zhaoxia;Mi Denghai;Wen Zhizhen;Yu Xinlin;Shao Peng;Wang Yongxiang(Department of Invasive Technology and Oncology,,the Second Hospital of Gansu Province,Lanzhou 730000,China;Department of Hematology,the Second Hospital of Gansu Province,Lanzhou 730000,China;Department of Plastic Surgery,the Second Hospital of Gansu Province,Lanzhou 730000,China;The First Clinical Medicine College of Lanzhou University,Lanzhou 730000,China)
出处
《临床荟萃》
CAS
2018年第4期323-328,共6页
Clinical Focus
基金
甘肃省卫生行业科研计划项目(GSWSKY-2014-14)
关键词
癌因性疲乏
影响因素
肺癌
问卷调查
cancer related fatigue
predictors
lung cancer
questionnaire
