摘要
目的探讨利多卡因软膏联合普瑞巴林胶囊治疗带状疱疹后遗神经痛的效果。方法选取2016年1月~2017年7月在我院门诊就诊的带状疱疹后遗神经痛患者84例,采用随机数字表法将其分为单一疗法组、联合疗法组,每组42例。单一疗法组单纯给予利多卡因软膏治疗,联合疗法组采用利多卡因软膏联合普瑞巴林胶囊治疗。比较两组带状疱疹后遗神经痛转归率;带状疱疹后遗神经痛消失时间;干预前后患者带状疱疹后遗神经痛程度、患者心理健康水平、社会功能、睡眠情况。结果联合疗法组带状疱疹后遗神经痛转归率高于单一疗法组,差异有统计学意义(P<0.05);干预前两组带状疱疹后遗神经痛程度、患者心理健康水平、社会功能、睡眠情况的比较,差异无统计学意义(P>0.05);干预后联合疗法组带状疱疹后遗神经痛程度、患者心理健康水平、社会功能、睡眠情况均优于单一疗法组,差异有统计学意义(P<0.05);联合疗法组带状疱疹后遗神经痛消失时间是(15.51±1.41)d,短于单一疗法组的(24.42±2.77)d,差异有统计学意义(P<0.05)。结论利多卡因软膏联合普瑞巴林胶囊治疗带状疱疹后遗神经痛的效果确切,可有效缓解疼痛,缩短病程,加速患者康复,促进患者生活质量提高,值得推广应用。
Objective To investigate the effect of Lidocaine Ointment combined with Pregabalin Capsules in the treatment of postherpetic neuralgia.Methods From January 2016 to July 2017,84 patients with postherpetic neuralgia were selected and randomly divided into single therapy group and combined therapy group,42 cases in each group.The single therapy group was treated with Lidocaine Ointment alone,and the combined therapy group was treated with Lidocaine Ointment combined with Pregabalin Capsules.The recovery rate of postherpetic neuralgia was compared between the two groups.The disappearance time of postherpetic neuralgia;degree of postherpetic neuralgia,mental health,social function and sleep status of patients before and after intervention were also compared.Results The recovery rate of postherpetic neuralgia in combination therapy group was higher than that in single therapy group,the difference was statistically significant(P<0.05).In the degree of postherpetic neuralgia,mental health,social function and sleep,there was no significant difference between the two groups(P>0.05).The degree of postherpetic neuralgia,mental health level,social function and sleep status in the combined therapy group were better than those in the single therapy group,the difference was statistically significant(P<0.05).The disappearance time of postherpetic neuralgia was(15.51±1.41)d in combination therapy group,which was shorter than that in single therapy group of(24.42±2.77)d,the difference was statistically significant(P<0.05).Conclusion The effect of Lidocaine Ointment combined with Pregabalin Capsules in the treatment of postherpetic neuralgia is exact,which can effectively relieve pain,shorten the course of disease,accelerate the recovery of patients and promote the quality of life of patients,which is worth popularizing and applying.
作者
罗宁
陆辉
LUO Ning;LU Hui(Department of Pain,Haicang Hospital of Xiamen City,Fujian Province,Xiamen 361026,China)
出处
《中国当代医药》
2018年第8期120-122,共3页
China Modern Medicine
