摘要
目的:探讨孕前优生健康检查及指导对合并乙肝病毒感染的人类免疫缺陷病毒(HIV)感染孕妇妊娠结局的影响。方法:回顾性分析2009年4月至2016年10月分娩的HIV合并感染乙肝病毒52例孕妇的妊娠结局,根据孕前是否进行优生健康检查及指导分为孕前优生健康检查及指导组(观察组)30例和未进行正规孕前健康检查及优生指导(对照组)22例。分析比较两组妊娠结局及孕妇对乙肝感染知识的影响。结果:观察组在干预后乙肝疾病的评分的优良率为70.00%,对照组为40.91%,两组患者比较差异有统计学意义(P<0.05);两组干预后对乙肝疾病知识的知晓率均较干预前有所升高,且观察组升高幅度较对照组大(P<0.05);观察组流产、死胎、早产儿、低体重儿和胎儿窘迫发生率分别为13.33%、16.67%、20.00%、13.33%和23.33%,对照组分别为40.91%、45.45%、50.00%、40.91%和54.54%,两组患者妊娠结局相比差异均有统计学意义(P<0.05)。结论:孕前优生健康检查及指导不仅能提高合并乙肝病毒感染的HIV感染孕妇对乙肝相关知识的知晓率,还能提高妊娠结局,降低出生缺陷发生率。
Objective:To investigate the effect of Pre-pregnancy health examination and guidance in pregnant women with hepatitis B virus combined with HIV infection on pregnancy outcomes.Methods:The pregnancy outcomes of 52 pregnant women with hepatitis B virus combined with HIV infection from April 2009 to October 2016 were retrospectively analyzed and they were divided into the group with pre-pregnancy health examination and guidance(the observation group)(n=30)and the group without pre-pregnancy health examination and guidance(the control group)(n=22)according to the fact whether pre-pregnancy health examination and guidance were made,with the effect of the hepatitis B infection knowledge and the pregnancy outcomes in pregnant women analyzed and compared.Results:The excellent rate of the observation group after the intervention was 70%,better than that of the control group(40.91%),the difference being statistically significant(P<0.05).After the intervention,the awareness rate of hepatitis B disease knowledge in the two groups was higher than that before intervention,and that of the observation group was significantly higher than that of the control group,the difference being statistically significant(P<0.05).The rates of abortion,stillbirth,premature birth,low birth weight and fetal distress in the observation group were 13.33%,16.67%,20.00%,13.33%and 23.33%respectively,and those in the control group were 40.91%,45.45%,50.00%,40.91%and 54.54%respectively,the differences in pregnancy outcomes being statistically significant(P<0.05).Conclusion:Pre-pregnancy health examination and guidance can not only improve the knowledge of the pregnant women with hepatitis B virus combined with HIV infection on hepatitis B virus infection,but also improve the outcome of pregnancy and reduce the incidence of birth defects.
作者
汤恋花
彭忠秀
李晶
郭晓峰
尹艳艳
TANG Lianhua;PENG Zhongxiu;LI Jing;GUO Xiaofeng;YIN Yanyan(The Eighth People's Hospital,Guangdong,Guangzhou 510000,China)
出处
《包头医学院学报》
CAS
2018年第3期94-97,共4页
Journal of Baotou Medical College
关键词
妊娠结局
乙肝病毒
HIV孕妇
优生
健康检查
Pregnancy outcome
Hepatitis B virus
Pregnant women with HIV infection
Pre-pregnancy health examination
