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Solitaire支架血管内取栓治疗急性基底动脉闭塞5例报道并文献复习

Mechanical thrombectomy with the Solitaire device in treating acute basilar artery occlusion among five patients and literature review
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摘要 目的探讨Solitaire支架取栓治疗急性基底动脉闭塞的安全性及有效性。方法回顾性分析2016年5月-2017年5月我院5例应用Solitaire支架血管内机械取栓方法的临床资料,分析患者治疗前后美国国立卫生院卒中量表(NIHSS)评分及出院时和术后30d的m RS评分,评估患者预后情况。结果 5例患者均取栓成功,术后即刻的DSA提示血管再通(TIMI2-3)率达100%;1例术后的NIHSS评分较术前明显改善,3例无明显变化,1例增高5分;1例术后30d m RS评分0分,2例4分,死亡2例;1例发生出血转化。结论 Solitaire支架取栓治疗BAO可以快速有效的使血管再通,但患者预后较差。综合评估侧枝循环状态和梗塞形成的部位及范围是判断BAO预后的关键。 Objective To explore the safety and efficacy of mechanical thrombectomy with Solitaire device in patients of acute basilar artery occlusion(BAO).Methods Retrospectively analyzed the clinical dates of five patients with acute basilar artery occlusion were treated with using Solitaire stent between May 2016 and May 2017,Neurologic status was evaluated before and after treatment according to the National Institutes of Health Stroke Scale(NIHSS),and mRS score on discharged and 30 days after treatment.Results Successful recanalization was achieved in all patients.Compared with pre-operation,the NIHSS score was significantly improved in 1 case,3 cases showed no significant changes and 1 case was increased to 5 points.The mRS score was 0 in 1 case,2 cases were 4 and two patients died at 30 days after surgery.Hemorrhagic transformation occurred in one patients.Conclusion In spite of mechanical thrombectomy with the Solitaire stent can recanalized the occluded basilar artery quickly and successfully,the patient's prognosis was still poor.As a result,we considered that comprehensive evaluation included collateral circulation statue,location and extent of infarction formation maybe the key to determine the prognosis of BAO.
作者 黄小飞 周小兵 陈岩 赵业禹 汪阳 HUANG Xiaofei;ZHOU Xiaobing;CHEN Yan;ZHAO Yayu;WANG Yang(First Affiliated Hospital of Nanchang University,Nanchang,330006,China)
出处 《江西医药》 CAS 2018年第3期189-193,共5页 Jiangxi Medical Journal
基金 国家自然科学基金项目(81471167) 江西省科技厅项目(20161BBI90018)
关键词 基底动脉闭塞 卒中 支架 机械取栓 basilar artery occlusion Stroke Stent Mechanical thrombectomy
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