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鸭坦布苏病毒江西分离株全基因组序列分析 被引量:4

Genetic Characteristics of Duck Tembusu Virus Isolated in Jiangxi
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摘要 为了解江西省鸭坦布苏病毒(Duck Tembusu virus,DTMUV)的遗传变异情况,对2013年江西省某蛋鸭场分离获得的1株鸭坦布苏病毒(命名为YF株)进行基因组分子特征及遗传进化分析。序列分析表明,该株病毒基因组全长10 990nt,未出现核苷酸插入或缺失及基因重组的变异情况,与已报道的DTMUV分离株的核苷酸同源性均在98.5%以上,且亲缘关系与当前鸭群中优势病毒亚群非常近。以上结果表明,近年来江西鸭群中流行的鸭坦布苏病毒遗传比较稳定,未发生变异。 Genetic characteristics and variation of the epidemic strain of duck Tembusu virus(DTMUV)found in Jiangxi Province were investigated.A DTMUV strain,designated as YF,was isolated from a clinical case in 2013.A sequence analysis showed the viral genome of YF to be 10,990 nt in length with no Ins/Del or genetic recombination.It shared no less than 98.5%homology with the viral strains isolated from ducks since 2010.Phylogenetically,YF had a close relationship with currently circulating dominant virus lineage.It appeared that the DTMUV in local ducks had been genetically stable throughout these years.
作者 刘烈发 叶林方 吴浩 黄烨祯 谢玉萍 刘远超 高琳 LIU Lie-fa;YE Lin-fang;WU Hao;HUANG Ye-zhen;XIE Yu-ping;Yuan-chao;GAO Lin(Jiangxi Animal Disease Prevention and Control Center,Nanchang,Jiangxi 330029,China)
出处 《福建农业学报》 CAS 北大核心 2018年第1期7-11,共5页 Fujian Journal of Agricultural Sciences
基金 江西省科技计划农业领域重点项目(20151BBF60049)
关键词 鸭坦布苏病毒 YF株 全基因组 序列分析 duck tembusu virus YF strain complete genome sequence analysis
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