摘要
目的:观察阿奇霉素不良反应情况,探寻科学有效的预防措施,保证治疗效果和用药安全性。方法:回顾性分析我院2014年7月~2017年1月收治的700例慢性感染急性发作或急性细菌感染患者的临床资料,给予阿奇霉素静脉滴注治疗,对不良反应进行分析,并制定防治措施。结果:700例患者中86例发生药物不良反应,不良反应发生率为12.29%,胃肠道不良反应发生率为84.88%(73/86),其次为低血压、变态反应、肝损害、关节疼痛等。结论:阿奇霉素治疗过程中主要表现出胃肠道不适等不良反应,临床需给予高度重视并采取科学防治措施,以保证用药安全和生命安全。
Objective:To observe the adverse reactions of azithromycin,to explore the scientific and effective preventive measures to ensure the effectiveness of treatment and drug safety.Methods:The clinical data of 700 patients with acute exacerbation or acute bacterial infection were analyzed retrospectively from July 2014 to January 2017.All patients were treated with intravenous infusion of azithromycin and the symptoms of adverse reactions were observed.Analysis,and the development of appropriate prevention and control measures.Results:The incidence of adverse reactions was 84.28%(73/86),followed by hypotension,allergy,liver damage,and the incidence of adverse reactions.The incidence of adverse reactions was 12.29%Pain and so on.Conclusion:Azithromycin treatment mainly shows gastrointestinal discomfort and other adverse reactions,clinical need to give high priority and take scientific prevention and control measures to ensure the safety of medication and patient safety.
作者
李要锋
Li Yaofeng(Department of Pharmacy,Hongli Hospital,Changyuan 453400,China)
出处
《北方药学》
2018年第4期7-8,共2页
Journal of North Pharmacy
关键词
不良反应
阿奇霉素
临床观察
Adverse reaction
Azithromycin
Clincal observation
