摘要
目的探讨宫颈癌筛查中有宫颈糜烂样改变妇女的人乳头瘤病毒(HPV)感染情况、细胞学结果及三者之间的关联。方法采用回顾性分析,选择在某三甲医院进行宫颈防癌筛查的年龄在29~55岁之间的5 513名女性,根据宫颈有无糜烂样改变将其分为观察组(宫颈糜烂样改变者)1 386例组,对照组(宫颈光滑组)4 127例,观察两组HPV及细胞学结果。结果观察组HPV感染率为11.46%,对照组为10.46%,两组比较差异无统计学意义,观察组细胞学结果异常21例(1.23%);对照组细胞学结果异常46例(1.11%),两组差异无统计学意义;观察组和对照组中,细胞学结果中度以上炎症分别为301例及444例,两组差异有统计学意义(P<0.05)。结论宫颈糜烂样改变不会增加宫颈高危型HPV感染的机会及其致病力,但可能增加宫颈炎症的发生率。
Objective To investigate the infection status of human papillomavirus(HPV)/cytological results and its association of cervical erosion changes women in cervical cancer screening.Methods 5 513 women aged 29 to 55 those who Screened for cervical cancer screening at a third hospital were divided into observation group(cervical erosion change group)1 386 cases,control group(smooth cervical group)4 127 cases,The retrospective analysis was be used to obsive the HPV and cytological results of two groups.Results The HPV infection rate was 11.46%in the observation group,10.46%in the control group,and there was no statistically significant difference between the two groups.Observation group cytological results were abnormal in 21 cases(1.23%).The results of cytological results in the control group were 46(1.11%),and the differences in the two groups were statistically significant.In the observation group and control group,there were 301 cases and 444 cases in the cytological results,respectively,and the differences in the two groups were statistically significant(P<0.05).Conclusion Cervical erosion change do not increase the risk of HPV infection in the cervix and their pathogenicity,but may increase the incidence of cervical inflammation.
作者
夏小艳
叶枫
周小明
Xia Xiaoyan;Ye Feng;Zhou Xiaoming(Department of Research,Changsha Health Vocational College,Changsha,Hunan,410100,China;Department of Clinical Medical,Changsha Health Vocational College,Changsha,Hunan,410100,China;Department of Internal Medicine,The First Affiliated Hospital of Hunan University of Chinese Medicine,Changsha,Hunan,410017,China)
出处
《当代医学》
2018年第10期39-41,共3页
Contemporary Medicine
