摘要
短暂性脑缺血发作(TIA)为一种病因复杂的综合性疾病,是由局灶性脑或视网膜缺血所致的短暂可逆性神经功能障碍,发作时仅持续数分钟,多在30 min内完全恢复,TIA频发会导致缺血性脑卒中,甚至出现不可逆性神经功能损害,因此明确TIA发病危险因素、分析其发病病因与机制有重要意义。目前认为TIA的发病机制为:在颈内动脉、椎基底动脉粥样硬化基础上,微栓塞及血流动力学、血液黏稠度、血液凝固性改变导致脑、脊髓、视网膜等部位局灶性缺血,继而出现短暂性神经功能缺损。随研究不断深入及神经影像学发展,人们对TIA的认识已发生很大变化,本文通过阅读近几年相关文献,对TIA发作危险因素、发作病因、发展进程、诊断技术、治疗方案研究现状作出论述,呈现TIA的研究成果。
Transient ischemic attack(TIA),a comprehensive disease with complex disease causes,is transient reversible neurological dysfunction caused by focal brain or retinal ischemia.The attack lasts for only a few minutes and normal function can be fully restored within 30min.Frequent TIA can lead to ischemic stroke,or even irreversible neurological impairment,so it is of practical significance to identify the risk factors for TIA occurrence and analyze its etiology and mechanism.It is believed that the pathogenesis of TIA is that following the atherosclerosis in the internal carotid artery and vertebrobasilar artery,the microembolization,hemodynamics,blood viscosity and blood coagulation changes can lead to focal ischemia in the brain,spinal cord,retina and other parts,followed by transient neurological function defect.With the increase of research and development of neuroimaging,people's understanding of TIA has changed a lot.By reading the related literature in recent years,this paper discusses the current research on TIA in terms of risk factors,etiology,progression,diagnostic technology and treatment plans in order to present the research findings of TIA
作者
李春
黄波
韦朝阳
LI Chun;HUANG Bo;WEI Chaoyang(Department of Neurology,Guangxi Brain Hospital,Liuzhou Guangxi 545005,China)
出处
《解放军预防医学杂志》
CAS
2018年第2期279-282,共4页
Journal of Preventive Medicine of Chinese People's Liberation Army
基金
广西壮族自治区卫生厅基金项目(No.Z2014188)
关键词
短暂性脑缺血发作
病因
进展
transient ischemic attack
etiology
advances
