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中药温阳健脾汤治疗便秘疗效观察及肠蛋白表达的影响 被引量:1

Observation on treating constipation with the Wenyang Jianpi decoction and expression of intestinal protein
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摘要 目的:探讨中药温阳健脾汤对便秘的治疗效果以及对肠蛋白表达的影响。方法:选取2015年4月-2016年4月我院接收的120例便秘患者并随机分组,对照组患者给予常规的西医治疗,实验组患者给予中药温阳健脾汤进行治疗,观察两组患者的治疗效果以及肠道中c-kit蛋白、SCF蛋白表达的变化情况,并进行比较。结果:根据评价标准评估患者的治疗效果,发现实验组治愈患者的例数明显比对照组多,实验组的治疗效率明显优于对照组,存在统计学差异;同时利用蛋白质定量检测法测定患者肠道中c-kit蛋白以及SCF蛋白的变化情况,发现经过治疗实验组患者上述两种蛋白的表达水平明显高于对照组,P<0.05,存在统计学差异。结论:中药温阳健脾汤对便秘的治疗效果明显优于常规的西医治疗,也能提高c-kit、SCF两种肠蛋白的表达水平,具有较高的临床应用价值,值得进一步推广。 Objective:To study the effect of the Wenyang Jianpi decoction(温阳健脾汤)on constipation and its expression of intestinal protein.Methods:120 cases were randomly divided into two group.The control group was treated with conventional western medicine;the experimental group was treated with the Wenyang Jianpi decoction.The efficacy,the expression of c-kit protein and SCF protein were observed and compared.Results:The cases of cure and efficiency in the experimental group were significantly better than the control group,with significant differences.The expression of c-kit protein and SCF protein were significantly higher than the control group,P<0.05.Conclusion:The Wenyang Jianpi decoction on constipation is superior to conventional western medicine,can improve the expression of c-kit protein and SCF protein,with high clinical value,and is worthy of promotion.
作者 耿晓敏
出处 《中医临床研究》 2018年第5期44-46,共3页 Clinical Journal Of Chinese Medicine
关键词 中药 温阳健脾汤 便秘 肠蛋白表达 TCM medicine The Wenyang Jianpi decoction Constipation The expression of intestinal protein
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