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骨搬移并发症对接点不愈合的研究与进展 被引量:11

Complications associated with bone transport: a literature review of nonunion at the docking site
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摘要 背景:Ilizarov骨搬移技术是治疗长骨大段骨缺损的有效方法,但对接点的不愈合是骨搬移治疗过程中最常见的并发症。目的:就Ilizarov骨搬移技术对接点的研究现状及临床治疗作一综述。方法:应用计算机检索CNKI和Pub Med数据库中关于对接点、截骨端、骨缺损及骨搬移相关的文章,在标题和摘要中以"对接点,骨搬移,骨缺损,Ilizarov"或"docking site,bone transport,bone defects,Ilizarov"为检索词进行检索。最终选择44篇重要文献进行综述。结果与结论:对接点的愈合周期被认为是决定骨搬移治疗周期长短的关键。针对对接点的愈合困难,各临床医师有不同的侧重处理办法,有的侧重于预防,有的侧重于生物治疗,有的侧重于手术干预。目前治疗对接点不愈合的方法有生物物理治疗、保守治疗和手术治疗。骨皮质剥脱术、关节镜下清创等微创治疗方式的出现,为对接点不愈合的治疗提供了更多的选择。而如何促进对接点的骨化愈合、缩短治疗周期是进一步研究的重点问题。 BACKGROUND:Bone transport is a powerful tool described by Ilizarov,which is an excellent biological method for the correction of large bone defects.But complications specifically associated with bone transport including delayed union or nonunion at the docking site occur frequently.OBJECTIVE:To analyze the research status and clinical treatments of the delayed union or nonunion at the docking site in bone transport using Ilizarov method.METHODS:A computer-based search of CNKI and PubMed databases was performed for the articles related to the docking site,osteotomy,bone defects and bone transport with the keywords of“docking site,bone transport,bone defects,Ilizarov”in English and Chinese,respectively.Finally,44 eligible articles were included to review.RESULTS AND CONCLUSION:Docking sites are the result of a classic bone transport technique for dealing with bone loss.Union may prove to be the rate-limiting step of this surgical procedure.About the delayed union or nonunion at the docking site,different clinicians have different foci,some clinicians focus on prevention,some focus on the biological treatment,and some focus on surgical intervention.The emergence of decortications and debridement under arthroscopy provides a new treatment strategy for the delayed union or nonunion at the docking site.How to promote the healing at the docking site and shorten treatment course still needs a further investigation.
作者 梁斌 张锴 Liang Bin;Zhang Kai(Department of Traumatic Orthopedics,Binzhou Medical University Hospital,Binzhou 256600,Shandong Province,China)
出处 《中国组织工程研究》 CAS 北大核心 2018年第8期1275-1280,共6页 Chinese Journal of Tissue Engineering Research
关键词 骨移植 骨折 骨折愈合 组织工程 Bone Transplantation Fractures,Bone Fracture Healing Tissue Engineering
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