摘要
辅助生殖技术(assisted reproductive technology,ART)是治疗不孕症的重要手段,胚胎成功着床是ART获得成功妊娠的关键因素之一。着床是胚胎黏附和侵入子宫内膜的过程,而正常形态的宫腔和子内膜是胚胎着床和维持妊娠的关键;子宫异常(包括先天性子宫发育异常及各种后天性子宫病理状态)可导致胚胎着床失败和妊娠失败。本文通过文献复习,介绍对ART助孕结局有影响的各类型子宫因素,包括薄型子宫内膜、子宫内膜息肉、宫腔粘连、子宫肌瘤、子宫腺肌病、子宫内膜蠕动波、子宫畸形、子宫内膜血流灌注,旨在进一步探讨如何改善ART的临床结局。
Assisted reproductive technology(ART)is one of the most important therapeutic measures for infertile couples,and embryonic implantation is one of the pivotal taches for the successful pregnancy of ART.Embryonic implantation is defined as the procedure of embryonic adhering and intruding into endometrium,so the uterine cavity and endometrium are very important for successful embryonic implantation and pregnancy.Abnormalities of uterus,including those congenital abnormalities and posteriority pathological states,could result in the failing embryonic implantation and pregnancy.In this review,those uterine factors related to the outcomes of ART were summarized,including thin endometrium,endometrial polyps,intrauterine adhesion,uterine fibroids,adenomyosis,endometrial peristalsis wave,uterine malformations and endometrial blood flow perfusion,so as to investigate the embryonic implantation and to improve the clinical outcomes of ART.
作者
袁月
杨媛
何晓霞
张学红
YUAN Yue;YANG Yuan;HE Xiao-xia;ZHANG Xue-hong(Key Laboratory of Reproductive Medicine and Embryo in Gansu,Reproductive Medicine Specialist Hospital,The First Hospital of Lanzhou University,Lanzhou 730000,China)
出处
《国际生殖健康／计划生育杂志》
CAS
2018年第2期132-136,共5页
Journal of International Reproductive Health/Family Planning
关键词
生殖技术
辅助
不育
女(雌)性
子宫
子宫疾病
治疗
Reproductive techniques,assisted
Infertility,female
Uterus
Uterine diseases
Therapy
