摘要
目的:探讨甲状腺全切术与次全切术对双侧结节性甲状腺肿的治疗效果。方法:选取双侧结节性甲状腺肿患者75例,根据住院号末尾数字奇偶分为对照组37例和观察组38例。对照组行甲状腺全切术,观察组行甲状腺次全切术,术后均给予甲状腺激素片替代治疗,并随访1年。观察两组手术相关指标、临床疗效、术后并发症及复发率,采用简明健康测量表(SF-36)评价患者生活质量。结果:观察组手术时间、术中出血量及住院时间均显著性低于对照组(P<0.05或P<0.01);治疗后对照组总有效率97.30%,观察组总有效率100.00%,两组总有效率比较差异无统计学意义(P>0.05);术后6个月,两组复发率无显著性差异(P>0.05);对照组并发症发生率显著性高于观察组(P<0.05);治疗后两组患者各项SF-36评分均高于治疗前,且观察组显著性高于对照组(P<0.05或P<0.01)。结论:甲状腺全切术与甲状腺次全切术均可有效治疗双侧结节性甲状腺肿,甲状腺次全切术对患者机体损伤小,术后并发症少、恢复快,值得临床推广应用。
Objective:To study the curative effect of total thyroidectomy and subtotal thyroidectomy in the treatment of bilateral nodular goiter.Methods:75 patients with bilateral nodular goiter were divided into control group{n=31)and observation group(n=38)according to the parity at the end of the hospital number.The control group underwent total thyroidectomy while the observation group underwent subtotal thyroidectomy.All patients received postoperative thyroid hormone replacement therapy,and were followed up for one year.The surgery-related indicators,curative effect,postoperative complications and recurrence rate were observed in the two groups.The quality of life was assessed by SF-36.Results:The operative time,intraoperative blood loss and length of stay in the observation group were significantly lower than those in the control group(P<0.05 or P<0.01).The total effective rates of the control group and the observation group were 97.30%and 100.00%,respectively(P>0.05).There was no significant difference in recurrence rate six months after treatment between the two groups(P>0.05).The incidence of complications in the control group was significantly higher than that in the observation group(P<0.05).The scores of SF-36 in the two groups after treatment were all higher than those before treatment,and the observation group showed higher score of SF-36 than the control group(P<0.05 or P<0.01).Conclusion:Both total thyroidectomy and subtotal thyroidectomy can effectively treat bilateral nodular goiter.Subtotal thyroidectomy has small injury to the body,fewer complications,and rapid recovery,which is worthy of clinical use.
作者
杨更光
张聪敏
YANG Gengguang;ZHANG Congmin(Department of General Surgery,Seventh Peoples Hospital of Zhengzhou,Zhengzhou,Henan 450047,China)
出处
《现代临床医学》
2018年第2期96-98,共3页
Journal of Modern Clinical Medicine
