摘要
微量元素是维持人体正常新陈代谢和生命活动的重要物质,对于人体健康的影响非常复杂,部分高浓度微量元素可能对人体有害,而必须微量元素的过度消耗,则可能会导致由酶功能障碍引起的人体代谢平衡失调。随着工业化的快速发展和技术进步,越来越多的重金属通过排污扩散到环境中,空气、水、土壤受到不同程度的污染。这些扩散到环境中的重金属可能造成一种或多种微量元素在人体体液内的含量失调而导致人体代谢紊乱。因此,掌握人体微量元素检测的关键技术,能准确了解人体内微量元素的平衡状态。本文旨在比较与微量元素检测相关的各种检测技术,探讨微量元素检测临床应用中面临的若干问题,为微量元素在临床检测的开展提供理论支持和技术指导。
Trace elements play an important role in maintaining human metabolism and life activities,and affect human health in a complicated way.Excessive intake of certain trace elements might be toxic to human whereas inadequate intake of essential elements may lead to human metabolic disorders caused by enzyme dysfunction.With the rapid development of industrialization and technology,more and more heavy metal components have been spread into the environment through the sewage disposal,which result in varying degrees of air,water and soil pollution as well as metabolic disorders due to one or more trace elements imbalances in body fluids.Using key techniques for determining the trace elements can identify the balance status of trace elements in human body.In this paper,we compared the characteristics and application challenges of various techniques related to trace element determination,aiming to provide theoretical support and technical guidance for clinical use of such determinations.
作者
熊婵
黎庆
马庆伟
XIONG Chan;LI Qing;MA Qing-wei(Institute of Chemistry,Graz University,Graz 8010,Austria;Bioyong Technology Inc,Beijing 102206,China;Academy for Advanced Interdisciplinary Studies,Peking University,Beijing 100871,China)
出处
《中国全科医学》
CAS
北大核心
2018年第8期888-895,共8页
Chinese General Practice
基金
国家"863"计划资助项目(2014AA022305
2014AA020901)
关键词
微量元素
医学检验科学
参考值
电感耦合等离子体质谱法
Trace element
Medical laboratory science
Reference values
Inductively coupled plasma-mass spectrometry
