摘要
目的观察阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apnea hypopnea syndrome,OSAHS)与心律失常及原发性高血压(高血压)的相关性。方法以2014年3月至2015年6月在南京市第一医院经多导睡眠监测(polysomnography,PSG)最终确诊为OSAHS的患者108例,按照有无高血压将其分为观察组(高血压组)及对照组(无高血压组),各54例。经体格检查及PSG记录患者的睡眠呼吸暂停低通气指数(apnea hypopneaindex,AHI)、心律失常次数及高血压分级,比较两组上述指标之间的差异并分析相互间的关系。结果 OSAHS与高血压分级(Ⅰ、Ⅱ、Ⅲ级)及心律失常发生率呈正相关(r=0.412、0.385、0.376和0.413,P<0.05)。两组的最慢心率及平均心率变化有明显异常,且高血压并发OSAHS患者的变化更大,差异具有统计学意义(P<0.05)。观察组窦性心动过速[27.78%(15/54)vs.9.26%(5/54),P<0.05]、室性心律失常[46.30%(25/54)vs.22.22%(12/54),P<0.05]、传导阻滞[74.07%(40/54)vs.55.56%(30/54),P<0.05]、窦性心动过缓[96.30%(52/54)vs.59.26%(32/54),P<0.05]、心房颤动[18.52%(10/54)vs.7.41%(4/54),P<0.05]的发生率明显高于对照组,差异具有统计学意义。结论高血压并发OSAHS患者的心律失常发生率明显增高,尤其是窦性心动过缓及心房颤动的发生率显著升高。
Objectives To observe the relationships between obstructive sleep apnea hypopnea syndrome(OSAHS)with cardiac arrhythmia and hypertension.Methods Totally108patients diagnosed as OSAHS by polysomnography(PSG)in Nanjing First Hospital from March2014to June2015were selected.According to whether they were with hypertension or not,the patients were divided into observation group(hypertension group)and control group(no hyper?tension group),each of54cases.Sleep apnea hypopnea index(AHI),incidence of arrhythmia and classification of hypertension were recorded by physical examination and PSG monitoring.They were compared and analyzed between the two groups.Results There were positive correlations between OSAHS with classification of hypertension(Ⅰ,Ⅱ,Ⅲgrade)and incidence of arrhythmia(r=0.412,0.385,0.376and0.413,P<0.05).Changes of slowest heart rate and average heart rate in the two group were both obvious,but they were more obvious in patients with OSAHS and hyper?tension(P<0.05).Incidences of nodal tachycardia[27.78%(15/54)vs.9.26%(5/54),P<0.05],ventricular arrhythmia[46.30%(25/54)vs.22.22%(12/54),P<0.05],heart-block[74.07%(40/54)vs.55.56%(30/54),P<0.05],sinus bradycardia[96.30%(52/54)vs.59.26%(32/54),P<0.05],atrial fibrillation[18.52%(10/54)vs.7.41%(4/54),P<0.05]in observation group were significantly higher than those in control group.Conclusions Incidence of arrhythmia,especially those of sinus tachycardia and atrial fibrillation,in patients with hypertension and OSAHS significantly increases.
作者
金晓萍
马玉玲
王海燕
潘立群
JIN Xiao-ping;MA Yu-ling;WANG Hai-yan;PAN Li-qun(Department of Internal Medicine-Cardiovascular,Nanjing First Hospital,Nanjing 210006,China)
出处
《岭南心血管病杂志》
2018年第1期57-59,95,共4页
South China Journal of Cardiovascular Diseases
关键词
高血压
阻塞性睡眠呼吸暂停综合征
心律失常
Objectives To observe the relationships between obstructive sleep apnea hypopnea syndrome(OSAHS)
