摘要
目的探索比索洛尔对慢性心力衰竭患者心率及神经内分泌因子昼夜节律的影响性。方法选取2014年3月12日—2016年3月12日我院慢性心力衰竭100例患者,抽签化分为对照组和观察组,每组各50例。对照组和观察组分别采用常规治疗和比索洛尔治疗。结果观察组患者的LVEDD(48.39±2.54)mm、LVESD(30.52±1.16)mm、LVEF(56.12±5.54)%、日间心率(72.15±2.13)次/min,均高于对照组,夜间心率(61.45±2.38)次/min、醛固酮(0.15±0.12)μg/L、肾上腺素(72.15±1.65)ng/L、NE(236.89±9.85)ng/L、Ang II(72.15±5.69)ng/L,低于对照组,差异具有统计学意义(P<0.05)。结论对慢性心力衰竭患者实施比索洛尔治疗效果显著,能够改善心率昼夜节律性。
Objective To explore the effect on heart rate of bisoprolol in patients with chronic heart failure and neuroendocrine circadian rhythm.Methods100cases of chronic heart failure in our hospital from March12,2014to March12,2016were selected.The draw was divided into the control group and the observation group,with50cases in each group.The control group and the observation group were treated with routine treatment and bisoprolol respectively.Results The LVEDD(48.39±2.54)mm,LVESD(30.52±1.16)mm,LVEF(56.12±5.54)%and daytime heart rate(72.15±2.13)times/min in the observation group were all higher than those in the control group.Night heart rate(61.45±2.38)times/min,aldosterone(0.15±0.12)μg/L,adrenalin(72.15±1.65)ng/L,NE(236.89±9.85)ng/L,Ang II(72.15±5.69)ng/L,the difference was statistically significant lower than that of the control group(P<0.05).Conclusion The effect of bisoprolol on patients with chronic heart failure is significant,and it can improve circadian rhythm of heart rate.
作者
詹龙亮
李国富
ZHAN Longliang;LI Guofu(Cardiology Department,Chongqing Tongliang District People's Hospital,Chongqing 402560,China)
出处
《中国继续医学教育》
2018年第8期119-121,共3页
China Continuing Medical Education
关键词
比索洛尔
慢性心力衰竭
心率
bisoprolol
chronic heart failure
heart rate
