摘要
目的:分析阿卡波糖对比二甲双胍治疗2型糖尿病(T2DM)的有效性、安全性和经济性。方法:选择我院2013年10月1日至2014年10月1日收治的92例2型糖尿病患者,分为A组与B组两组,每组各46例。其中对A组采取二甲双胍治疗,B组采用阿卡波糖治疗。结果:A组与B组的治疗总有效率分别为84.78%与82.61%,P>0.05;A组与B组的不良反应发生率分别为13.04%与15.22%,P>0.05;A组具有较为明显的经济学优势,P<0.05;比较两组治疗前后的餐后血糖(FPG)、餐后2h血糖(2h PG)、糖化血红蛋白(Hb Alc)水平无明显差异,P>0.05。结论:对2型糖尿病患者采取二甲双胍与阿卡波糖进行治疗均可获得较为明显的疗效,药物安全性均较高,且二甲双胍更为经济有效。
Objective:To analyze the efficacy,safety and economy of acarbose versus metformin in treatment of type2diabetes(T2DM).Methods:92patients with type2diabetes admitted by our hospital from October1,2013to October1,2014were divided into two groups:group A and group B,with46cases in each group.Group A was treated with metformin and group B was treated with acarbose.Results:The total effective treatment of group A and group B was84.78%and82.61%respectively,P>0.05.The incidence of adverse reactions in group A and group B was13.04%and15.22%respectively,P>0.05;Group A has obvious economic advantages,P<0.05.There was no significant difference between the FPG,HbAlc,and2hPG levels before and after treatment,P>0.05.Conclusion:The treatment of dimetformin and acapalose in type2diabetes mellitus can obtain more obvious curative effect,the drug safety is higher,and metformin is more economical and effective.
作者
张明
成立娟
任志学
郭敬
李红霞
宋玉玲
靳丽丽
刘晓宇
魏田静
ZHANG Ming;CHENG Lijuan;REN Zhixue;GUO Jing;LI Hongxia;SONG Yuling;JIN Lili;LIU Xiaoxu;WEI Tianjing(Department of Endocrinologya,the Seventh People′s Hospital of Hebei Province,Hebei Baoding073000,China;Department of Pediatricsb,the Seventh People′s Hospital of Hebei Province,Hebei Baoding073000,China;Department of Neurologyc,the Seventh People′s Hospital of Hebei Province,Hebei Baoding073000,China;Department of Internal Medicine,Dingzhou Hua Zhang Mongolia Medicine Hospital,Hebei Dingzhou073000,China)
出处
《中国医药导刊》
2017年第11期1168-1170,共3页
Chinese Journal of Medicinal Guide
基金
保定市科学技术研究与发展指导计划项目(项目编号:14ZF080
项目名称:二甲双胍与阿卡波糖对糖尿病下肢缺血性疾病临床疗效的研究)
