摘要
目的比较急性单纯性阑尾炎内镜下阑尾腔冲洗联合抗生素治疗与单纯抗生素治疗的临床效果。方法将78例符合纳入标准的急性单纯性阑尾炎患者按志愿原则分为内镜下阑尾腔冲洗联合抗生素治疗39例(观察组),单纯抗生素治疗39例(对照组),比较两种治疗方法的腹痛改善情况、抗生素使用时间、住院时间、并发症发生率、治愈率、复发率等指标。结果两组患者都能达到临床治愈,治愈率为100%。观察组患者第1、3、5天腹痛逐渐减轻直至消失,与对照组比较差异有统计学意义(P<0.001),观察组疗效优于对照组。观察组的腹痛消失时间、抗生素使用时间、住院时间均少于对照组,两组比较差异有统计学意义(P<0.05或0.01)。两组均无并发症。观察组复发1例,复发率为2.56%,对照组复发5例,复发率为12.82%,两组复发率比较差异无统计学意义(P>0.05)。结论与单纯抗生素治疗相比,内镜下阑尾腔冲洗联合抗生素治疗具有炎症消退时间短、病情恢复快、住院时间短等优点,是急性单纯性阑尾炎患者首选的治疗方式。
Objective To compare the clinical effects of endoscopic appendectomy combined with antibiotic and simple antibiotic in the treatment of acute simple appendicitis.Methods78patients with acute simple appendicitis who met the inclusion criteria were divided into endoscopic appendectomy combined with antibiotic group(observation group)and simple antibiotic group(control group)with39cases in each group according to the principle of volunteering.Then,the improvement of abdominal pain,antibiotic use time,length of hospital stay,complication rate,cure rate and recurrence rate,etc.were compared between the two methods of treatment.Results Both groups were able to achieve clinical cure,with a cure rate of100%.The abdominal pain in the observation group gradually decreased and then disappeared at the first,third and fifth day of treatment,compared with the control group,difference was statistically significant(P<0.001).The observation group had better effect than the control group.The disappearance time of abdominal pain,antibiotic use time,length of hospital stay of the observation group were all shorter than those of the control group,difference was statistically significant(P<0.05or0.01).No complications were found in the two groups.Recurrence was found in1case in the observation group,recurrence rate was2.56%,and5cases in the control group,recurrence rate was12.82%,difference was not statistically significant(P>0.05).Conclusion Compared with simple antibiotic,endoscopic appendectomy combined with antibiotic has the advantages of short duration of inflammation,rapid recovery and short hospitalization time,etc.It is the first choice for the treatment of acute simple appendicitis.
作者
陈德艺
韦良宏
陈海东
韦良鹏
沈丽丽
CHEN Deyi;WEI Lianghong;CHEN Haidong;EI Liangpeng;SHEN Lili(Digestive Medical Department,The First People’s Hospital of Qinzhou,Qinzhou 535000,China)
出处
《右江医学》
2017年第6期655-658,共4页
Chinese Youjiang Medical Journal
基金
广西壮族自治区卫生厅科研课题(Z2014577)
