摘要
目的:探讨营养摄入成分对脓毒症伴急性肾损伤病人血尿素氮(BUN)的影响。方法:回顾性分析20例脓毒症患者,其中10例为脓毒症伴急性肾损伤者(SAKI组),10例为脓毒症肾功能正常者(S组)。记录营养支持1 d和3 d后各成分的能量及病人血BUN水平,分析不同营养成分摄入量和血BUN的关系。结果:营养支持1 d及3 d后,S组和SAKI组碳水化合物、脂肪、氮物质供能及总能量差异无统计学意义,营养支持3 d后,SAKI组血BUN的增加值(△BUN)(10.9±4.3)μmol/L,高于S组的(4.4±2.4)μmol/L(P<0.01)。SAKI组患者BUN增加值与氮物质能量摄入呈高度线性相关(r=0.71)。结论:高含氮物质的摄入可能增加脓毒症伴急性肾损伤患者的血尿素氮水平。
Objective:To investigate the effects of nutrient intake on the blood urea nitrogen(BUN)level in patients with septic acute kidney injury.Methods:Twenty patients with sepsis were equally divided into septic acute renal injury group(group SAKI,n=10)and those without acute kidney injury group(group S,n=10)according to kidney function.Then two groups of patients were recorded regarding the energy content of each component in nutrient support after1day and3days and the BUN concentration.The relationship between nutrient intake and BUN level was analyzed.Results:There was no significant difference in the total energy and total energy of carbohydrates,fat and nitrogen level between group S and group SAKI after1day and3days of nutrition support.However,increased BUN level in group SAKI[(109±43)μmol/L]was significantly increased than that in the group S[(44±24)μmol/L]after3days of nutritional support(P<001).Increased BUN level and nitrogen intake were in highly linear correlation in group SAKI.Conclusion:High nitrogen intake may increase blood urea nitrogen levels in patients with septic acute kidney injury.
作者
肖石
陈群
鲁卫华
王箴
XIAO Shi;CHEN Qun;LU Weihua;WANG Zhen(Department of Critical Care Medicine,The First Affiliated Hospital of Wannan Medical College,Wuhu 241001,China)
出处
《皖南医学院学报》
CAS
2017年第6期532-534,共3页
Journal of Wannan Medical College
基金
安徽省自然科学基金项目(1608085MH199)
安徽省高校学科(专业)拔尖人才学术资助项目(GXBJZD19)
关键词
脓毒症
急性肾损伤
营养支持
血尿素氮
sepsis
acute kidney injury
nutrition support
blood urea nitrogen
