摘要
目的分析采用血脂康结合阿托伐他汀治疗高血压合并冠心病的临床疗效。方法选取宁夏固原市隆德县人民医院2016年4月～2017年4月接收并单纯行阿托伐他汀治疗的60例高血压合并冠心病患者作为对照组，再从同期接收并采取血脂康与阿托伐他汀结合治疗的同疾病患者60例作为研究组，对比2组的临床治疗疗效。结果对照组60例患者的临床治疗总有效率是75.00%，显著低于研究组的93.33%，2组比较差异具有统计学意义（P＜0.05）。治疗前2组患者的各项血脂指标水平对比均无统计学意义；经过不同方法治疗4w后除高密度脂蛋白无显著差异外，研究组的总胆固醇、甘油三酯以及低密度脂蛋白水平均明显低于对照组，比较差异具有统计学意义（P＜0.05）。结论对高血压并发冠心病患者积极采取血脂康结合阿托伐他汀治疗，能够显著降低总胆固醇、甘油三酯以及低密度脂蛋白等血脂指标的水平，全面提高临床疗效。
Objective To analyze the clinical effect of Xuezhikang combined with atorvastatin in the treatment of hypertension with coronary heart disease.Methods60patients with hypertension and coronary heart disease who received and treated with atorvastatin alone from April2016to April2017in Longde County People's Hospital as the control group,and another60patients at the same time as the study group,they were given Xuezhikang combined with atorvastatin,compared the two groups of clinical treatment.Results The total effective rate of clinical treatment in control group(75.00%)was significantly lower than that in study group(93.33%).There was significant difference between the two groups(P<0.05).There was no significant difference in serum lipid levels between the two groups before treatment.After4weeks of treatment,there was no significant difference in high-density lipoprotein and total cholesterol between two groups.Levels of triglyceride and low density lipoprotein in study group were significantly lower than the control group,there was significant difference between the two groups(P<0.05).Conclusion It is possible to reduce the levels of serum lipids significantly,such as total cholesterol,triglyceride and low density lipoprotein,and improved the clinical curative effect in patients with hypertension complicated with coronary heart disease.
作者
杜惠莲
DU Hui-lian(Department of Cardiovascular Medicine, People’s Hospital of Longde County, Guyuan 756300, China)
出处
《中国生化药物杂志》
CAS
2017年第11期455-456,458,共3页
Chinese Journal of Biochemical Pharmaceutics
关键词
血脂康
阿托伐他汀
高血压
冠心病
Xuezhikang
atorvastatin
hypertension
coronary heart disease
