摘要
妊娠过程异常不仅威胁孕母的健康,而且对新生儿出生情况、生长发育及生命后期都有着重要影响。随着医学技术的进步,新生儿的生存率在不断提高,早产儿以及低出生体重的新生儿逐渐增多。如何通过改变孕妇营养素摄入情况来减少不良妊娠的发生是营养学研究者的挑战之一。已有多项研究证明孕妇在孕早期或整个孕期服用叶酸可以降低先兆子痫的发生率,同时也有研究证明叶酸可以降低胎盘早剥、自然流产、宫内生长迟缓和早产的发生率。本研究就近几年国内外关于孕期叶酸补充情况和叶酸相关代谢酶基因多态性与先兆子痫、胎盘早剥、自然流产、宫内生长迟缓、早产等不良妊娠关系进行简要综述。
Abnormal pregnancy not only threatens maternal health,but also significantly impacts on the birth condition,growth and development and the quality of later life.With the advances in medical technology,neonatal survival rate continues to increase,and preterm children and low birth weight newborns gradually increase.How to reduce the incidence of adverse pregnancy by changing the nutrient intake of pregnant women is one of the challenges of nutrition researchers.Number of studies have proved that pregnant women who take in folic acid in the first trimester or throughout pregnancy can reduce the incidence of pre-eclampsia,while studies have shown that folic acid intake can also reduce the incidence of placental abruption,spontaneous abortion,intrauterine growth retardation,preterm birth
作者
王敌
华丽
成晨
王少康
Wang Di;Hua Li;Cheng Chen;Wang Shao-kang(Department of nutrition and food hygiene, School of public health, Southeast University, Key Laboratory of environmental science and engineering of Ministry of Education Jiangsu Province, Nanjing, Jiangsu, 210009, China;Maternal and child health care hospital of Jurong City, Jurong, Jiangsu, 212400, China)
出处
《当代医学》
2017年第33期180-183,共4页
Contemporary Medicine
基金
江苏省妇幼保健协会科研课题(FYX201504)
镇江市社会发展指导性项目及句容市民生科技计划项目(FZ2015067)
东南大学儿童发展与学习科学教育部重点实验室开放基金项目(CDLS-2016-04)
东南大学科研训练计划项目(201742017)
关键词
叶酸
先兆子痫
胎盘早剥
自然流产
宫内生长迟缓
早产
Folic acid
Preeclampsia
Placental abruption
Spontaneous abortion
Intrauterine growth retardation
Premature birth
