摘要
目的分析胸腔镜肺段切除术和肺叶切除术对早期非小细胞肺癌(non-small cell lung cancer,NSCLC)患者中远期预后的影响,旨在为临床治疗提供理论依据。方法回顾性分析本院2010年1月至2012年1月收治的86例早期NSCLC患者的临床资料。将患者按照治疗方式不同分为肺段切除组(43例)和肺叶切除组(43例)。比较两组患者手术出血量、住院费用、拔管时间、住院天数、胸腔引流量、术后并发症发生率及术后1年肺功能下降比率;随访5年,比较两组患者中远期生存情况。结果两组患者手术出血量、住院费用、拔管时间及术后并发症发生率比较均无显著差异(P>0.05),肺段切除组患者的住院天数和胸腔引流量均明显少于肺叶切除组(P<0.05),手术时间明显长于肺叶切除组(P<0.05);术后1年,肺段切除组患者肺功能下降比率明显低于肺叶切除组(P<0.05);两组患者术后中远期总生存率和无瘤生存率比较均无显著差异(P>0.05)。结论胸腔镜肺段切除术和肺叶切除术对早期NSCLC患者中远期预后的影响无显著差异,但胸腔镜肺段切除术具有住院天数短、术后胸腔渗出液少以及对患者肺功能影响小的优点。
Objective To investigate the medium and long term prognostic of patients with early stage nonsmall cell lung cancer(NSCLC)treated by thoracic segmental resection of lung and pulmonary lobectomy,to provide theoretical basis for clinical treatment.Method The clinical data of86patients with early stage non small cell lung cancer treated in our hospital from January2010to January2012were retrospectively analyzed,all patients were divided into segmental resection of lung group(n=43)and pulmonary lobectomy group(n=43)according to the treatment method.The amount of bleeding,hospitalization expenses,extubation time,hospital day,volume of thoracic drainage,postoperative complication rate and lung function decline rate1year after operation were compared between the two groups.Followed up for5years,survival rate of the two groups were observed.Result There were no significant differences in the amount of bleeding,hospitalization expenses,extubation time and postoperative complication rate of the two groups(P>0.05).The hospital day and volume of thoracic drainage of segmental resection of lung group was significantly less than that of pulmonary lobectomy group(P<0.05),the operation time was significantly longer than that of pulmonary lobectomy group(P<0.05).The lung function decline rate of lung and pulmonary lobectomy group1year after operation were significantly lower than that of pulmonary lobectomy group(P<0.05).There were no significant differences in medium and long term survival rate and tumor free survival rate between the two groups(P>0.05).Conclusion There is no significant difference between the effect of segmental resection of lung and lobectomy and pulmonary lobectomy on the long-term prognosis of patients with early-stage NSCLC,but segmental resection of lung has advantages of short hospital day,less postoperative pleural effusion and little effect on lung function.
作者
孙涛
顾江魁
胡一淼
陶立伟
葛阳
SUN Tao;GU Jiang-kui;HU Yi-miao;TAO Li-wei;GE Yang(Department of Thoracic Surgery, NO.2 People's Hospital of Fuyang City, Anhui, Fuyang 236015, China)
出处
《中国医学前沿杂志（电子版）》
2017年第8期86-89,共4页
Chinese Journal of the Frontiers of Medical Science(Electronic Version)
基金
"十二五"科技重大专项科研协作(2015ZX10003001-002)
关键词
早期
非小细胞肺癌
胸腔镜
肺段切除术
肺叶切除术
预后
Early
Non-small cell lung cancer
Thoracoscope
Segmental resection of lung
Pulmonary lobectomy
Prognosis
