摘要
目的:探讨腹腔镜辅助直肠癌根治术对患者炎性水平及应激反应的影响。方法:收治直肠癌患者96例,随机分为观察组44例和对照组52例。观察组行腹腔镜辅助直肠癌根治术,对照组行开腹直肠癌根治术。结果:术后2 d,观察组血糖、胰岛素、三碘甲状腺原氨酸、四碘甲状腺原氨酸、皮质醇水平与对照组比较,差异具有统计学意义(P<0.05);术后1 h、1 d、3 d,两组患者炎性反应相关指标水平呈先上升再回落的趋势,且观察组同期白细胞介素-6、肿瘤坏死因子、C反应蛋白及人生长激素释放肽水平均低于同期对照组的指标水平,差异具有统计学意义(P<0.05)。结论:腹腔镜辅助直肠癌根治术对患者炎性水平及应激反应的影响较开腹直肠癌根治术小,具有创伤小、疗效好等治疗优势。
Objective:To investigate the effect of laparoscopic assisted radical rectal resection and laparotomy on the level of inflammation and stress in patients undergoing open radical resection of rectal cancer.Methods:96patients with rectal cancer were selected.They were randomly divided into the observation group with44cases and the control group with52cases.The observation group underwent laparoscopic radical resection of rectal cancer.The control group underwent radical resection of rectal cancer.Results:In2days after surgery,the differences in blood glucose,insulin,triiodothyronine three,four triiodothyronine,cortisol levels in the observation group was statistically significant than in the control group(P<0.05);after1h,1d,3d,inflammation related indicators in the two groups was rised first and then fell again,and interleukin-6,tumor necrosis factor,C reactive protein and human growth hormone releasing peptide in the observation group were lower than those in the control group during the same period,and the differences were statistically significant(P<0.05).Conclusion:Laparoscopic assisted radical resection of rectal cancer has less influence on inflammatory level and stress response than laparotomy radical resection of rectal cancer.It has the advantages of less trauma and good curative effect.
作者
周志林
戴军
杨旭辉
梅勇
Zhou Zhilin;Dai Jun;Yang Xuhui;Mei Yong(Department of General Surgery,Liyuan Hospital Affillited to Tongji Medical College of Huazhong Science and Technology University,Wuhan City 430077)
出处
《中国社区医师》
2017年第25期21-22,24,共3页
Chinese Community Doctors
关键词
腹腔镜直肠癌根治术
炎性水平
应激反应
Laparoscopic radical resection of rectal cancer
Inflammatory level
Stress reaction
